يعرض 18,501 - 18,520 نتائج من 21,342 نتيجة بحث عن '(( significant health decrease ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.42s تنقيح النتائج
  1. 18501

    Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... حسب Wu Chen (569414)

    منشور في 2025
    "…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…"
  2. 18502

    Table 1_Effect of compound kushen injection on immune function in patients with colorectal cancer: a systematic review and meta-analysis.docx حسب Lixin Zhang (55947)

    منشور في 2025
    "…Chemotherapy and radiotherapy remain cornerstone treatments; however, they often lead to significant immune suppression and an increased risk of infection. …"
  3. 18503

    Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... حسب Wenjing He (4278625)

    منشور في 2025
    "…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …"
  4. 18504

    Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  5. 18505

    Data Sheet 1_Real world evidence of dupilumab effectiveness in a Colombian cohort of patients diagnosed with severe asthma.docx حسب Abraham Alí-Munive (21347201)

    منشور في 2025
    "…FEV<sub>1</sub>pp showed higher but not significant values from the 2–4-month period, with a median change of 12.5% (IQR: 0.3, 21.5). …"
  6. 18506

    Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  7. 18507

    Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  8. 18508

    Correlation analyses between studied genes. حسب Marwa A. Ali (11973086)

    منشور في 2024
    "…</p><p>Conclusions</p><p>Our study is the first to detect decreased <i>NEAT-1</i> and <i>miR374b-5p</i> expression in COVID-19 patients’ serum. …"
  9. 18509

    Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... حسب Wenlei Wang (1514554)

    منشور في 2024
    "…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…"
  10. 18510

    AjMLKL is involved in 10<sup>8</sup> CFU/mL AJ01 induced lytic coelomocyte death independent on its phosphorylation. حسب Kaiyu Chen (11691918)

    منشور في 2025
    "…Coelomocyte viability was significantly increased (L), and coelomocytes plasma membrane disruption (M) and the percentage of Annexin V+/PI+ coelomocytes significantly decreased (N). …"
  11. 18511

    Supplementary Material for: The current status of tumor markers as biomarkers in the era of immunotherapy for hepatocellular carcinoma: alpha-fetoprotein alone is not sufficient حسب Hiraoka A. (4273894)

    منشور في 2025
    "…Positive rates for AFP (67.8%, 62.1%, 50.8%, respectively) and DCP (84.1%, 80.5%, 72.7%, respectively) were decreased (each P<0.001), while the AFP-L3 rate did not show a significant change (54.4%, 57.7%, 51.9%, respectively P=0.390). …"
  12. 18512
  13. 18513

    Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx حسب Ping Zhao (47228)

    منشور في 2025
    "…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19<sup>+</sup> B cells and CD14<sup>+</sup> monocytes, but significantly decreased on CD56<sup>+</sup> NK cells.We identified a distinct CD226<sup>+</sup>CD19<sup>+</sup> B cell subset that exhibited pathogenic features in pSS. …"
  14. 18514

    Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p... حسب Wenlei Wang (1514554)

    منشور في 2024
    "…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…"
  15. 18515

    Effects of extracorporeal shock wave therapy on motor function in patients with cerebral palsy: a systematic review and meta-analysis حسب Hui-Hui Peng (21503736)

    منشور في 2025
    "…In addition, spasticity significantly decreases, particularly with focused ESWT or ESWT targeting the upper limbs.…"
  16. 18516

    SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation. حسب Dilara Koc (22431017)

    منشور في 2025
    "…<b>(C and D)</b> PMA treatment further decreases neurotransmitter release when a low level of SNAP-25 cleavage is present. …"
  17. 18517

    Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx حسب Ying Zhang (40767)

    منشور في 2025
    "…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …"
  18. 18518

    The role of SLMO in the PSS/PISD pathway. حسب Siwen Zhao (543384)

    منشور في 2024
    "…(C) SLMO overexpression failed to reverse decreased mitochondrial size from <i>pisd</i><sup><i>RNAi</i></sup> lines. …"
  19. 18519

    Supplementary file 6_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx حسب Ying Zhang (40767)

    منشور في 2025
    "…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …"
  20. 18520

    Supplementary file 1_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx حسب Ying Zhang (40767)

    منشور في 2025
    "…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …"