يعرض 61 - 80 نتائج من 44,650 نتيجة بحث عن '(( significant herg based ) OR ( significant ((we decrease) OR (mean decrease)) ))', وقت الاستعلام: 2.15s تنقيح النتائج
  1. 61
  2. 62

    Electrophysiological assays on human hERG potassium ion-channels. حسب Akos Nyerges (9461225)

    منشور في 2020
    "…<p>SD represents standard deviation based on <i>n</i> = 8. A reference hERG-inhibitor, E-4031 (Sigma-Aldrich) was included as a positive control and had a measured IC<sub>50</sub> of 0.033 μM. …"
  3. 63
  4. 64
  5. 65
  6. 66
  7. 67
  8. 68
  9. 69

    Supplementary Material for: Decreasing Attacks and Improving Quality of Life through a Systematic Management Program for Patients with Hereditary Angioedema حسب Nunes F.L. (10223465)

    منشور في 2021
    "…<b><i>Results:</i></b> Mean number of attacks/month significantly decreased (95% credible interval [CrI] excluding 0) from 1.15 preintervention to 0.25 and 0.23, 8 and 14 months within intervention, with mean decreases of −0.89 (95% CrI: −1.21 to −0.58) and −0.92 (95% CrI: −1.22 to −0.60), respectively. …"
  10. 70

    Table_1_Decreased Serum Brain-Derived Neurotrophic Factor Concentrations 72 Hours Following Marathon Running.DOCX حسب Astrid Roeh (11136600)

    منشور في 2021
    "…</p><p>Conclusion: Prolonged exercise induces a significant decrease in serum BDNF concentration 72 h post-exercise. …"
  11. 71

    Structure-Based Development of 3,4-Fused Tricyclic Benzofuran Derivatives as Polyketide Synthase 13 Inhibitors with Negligible hERG Inhibition حسب Yu-Xin Zhou (20837736)

    منشور في 2025
    "…The early lead benzofuran-3-carboxamide TAM16, demonstrated robust in vivo efficacy in murine models of tuberculosis infection; however, its further advancement was halted due to the cardiotoxicity associated with hERG inhibition. We implemented a conformational restriction strategy to explore the chemical space of 3,4-fused tricyclic benzofurans and indoles employing a structure-based design approach. …"
  12. 72

    Structure-Based Development of 3,4-Fused Tricyclic Benzofuran Derivatives as Polyketide Synthase 13 Inhibitors with Negligible hERG Inhibition حسب Yu-Xin Zhou (20837736)

    منشور في 2025
    "…The early lead benzofuran-3-carboxamide TAM16, demonstrated robust in vivo efficacy in murine models of tuberculosis infection; however, its further advancement was halted due to the cardiotoxicity associated with hERG inhibition. We implemented a conformational restriction strategy to explore the chemical space of 3,4-fused tricyclic benzofurans and indoles employing a structure-based design approach. …"
  13. 73

    DataSheet_1_Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.docx حسب Zijing Ran (11429935)

    منشور في 2021
    "…By multiple regression model, ΔSU was identified to be a significant determinant variable of decrease in VFA (beta, 0.302; p = 0.001).…"
  14. 74
  15. 75

    Image_3_Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress.tif حسب Nobuhiko Ebisutani (9764468)

    منشور في 2020
    "…The expression of both GN and UGN was significantly decreased in the CSDS mice relative to controls. …"
  16. 76

    Image_2_Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress.tif حسب Nobuhiko Ebisutani (9764468)

    منشور في 2020
    "…The expression of both GN and UGN was significantly decreased in the CSDS mice relative to controls. …"
  17. 77

    Image_1_Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress.TIF حسب Nobuhiko Ebisutani (9764468)

    منشور في 2020
    "…The expression of both GN and UGN was significantly decreased in the CSDS mice relative to controls. …"
  18. 78
  19. 79
  20. 80