Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Figure 3 from A Cost-Effective Two-Step Approach for Multi-Cancer Early Detection in High-Risk Populations حسب Shuaipeng Geng (20612220)

"…In the case–control cohort, the two-step MCED approach significantly improved specificity from 91.0% to 99.3%, whereas sensitivity decreased from 49.9% to 39.9%. …"

Data Sheet 1_The gastric microbiome altered by A4GNT deficiency in mice.zip حسب Dawei Gong (3070773)

"…The relative abundance of mutagenic Desulfovibrio and proinflammatory Prevotellamassilia in these mice was significantly increased, especially 4 weeks after birth. …"

Dataset visualization diagram. حسب Yaojun Zhang (389482)

"…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …"

Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes حسب Wenwei Liang (9286389)

"…In the osteoarthritis mouse model, they effectively decreased joint inflammation and increased the expression of chondrocyte markers.…"

The effect of G83R mutation on transthyretin protein structural stability حسب Xingwang Chen (11225802)

"…Molecular dynamics simulation suggested that the G83R mutation reduces the dynamic stability of TTR by increasing the molecule flexibility. In the thermodynamic stability, the quaternary and tertiary structural stability of TTR G83R is lower than wild-type TTR but significantly higher than TTR V30M. …"

Data Sheet 1_External and internal forcings controlled the precipitation patterns in eastern China over the past millennium.pdf حسب Hai Li (254910)

"…Our records indicate that the warm (cold) phase of the Atlantic Multidecadal Variability significantly increases (decreases) summer precipitation in North China through atmosphere-ocean feedback and circum-global teleconnection. …"

Table 1_External and internal forcings controlled the precipitation patterns in eastern China over the past millennium.xlsx حسب Hai Li (254910)

"…Our records indicate that the warm (cold) phase of the Atlantic Multidecadal Variability significantly increases (decreases) summer precipitation in North China through atmosphere-ocean feedback and circum-global teleconnection. …"

Data Sheet 1_Cellular respiration and amino acid metabolism is altered by dietary oligosaccharides in Salmonella with epithelial cell association.docx حسب Claire A. Shaw (22382332)

"…However, gene expression analysis revealed significantly induced expression of Specific Pathogenicity Island (SPI) 1 (adj. p < 2.0−6) and 2 (adj. p < 3.0−5) with HMO treatment, opposed to increased fimbriae expression (adj.p < 3.0−3) with MOS treatment. …"

Data Sheet 1_A glycogen derived from sea urchin-Strongylocentyotus internedius shifts macrophages to the M1 phenotype and enhances the anti-pancreatic cancer activity of gemcitabin... حسب Zhenzhen Deng (3707608)

"…MSGA-induced M1 macrophages decreased the cell viabilities and induced apoptosis of PDAC cells. …"

Dataset sample images. حسب Yaojun Zhang (389482)

"…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …"

Performance comparison of different models. حسب Yaojun Zhang (389482)

"…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …"

SPEED-ACCURACY TRADE-OFF PARADIGM IN COOPERATIVE TRANSPORT OF ANTS حسب N FC (19866297)

"…Regarding the efficiency estimators, we found that the consensus time decreases as the level of competition increases. Additionally, the ants exhibited more tortuous trajectories in all competitive scenarios compared to the distilled water control. …"

Table 1_Microbial community and flavor analyses of fermented grains of Furou-type Baijiu.docx حسب Yanyan Tang (250904)

"…The dominant bacterial species changed from Bacillus subtilis to Acetilactobacillus jinshanensis, and the dominant fungal genus, Saccharomyces sp., gradually increased. The relative abundance of Wickerhamomyces anomalus gradually decreased. …"

Data_Sheet_1_Responses of diazotrophic network structure and community diversity to alfalfa-maize intercropping are soil property-dependent.docx حسب Jinglei Zhang (311803)

"…However, in the average soil, it was the A/M system that had an altered diazotrophic structure, with an increased abundance of 11 bacterial genera and a decreased abundance of three bacterial genera (p < 0.05).…"

Data Sheet 1_Endothelial Zmiz1 modulates developmental angiogenesis in the retina.pdf حسب Nehal R. Patel (18522672)

"…Inducible endothelial cell-specific ablation of Zmiz1 postnatally resulted in impaired retinal vascular outgrowth, decreased vascular density, and increased vessel regression. …"

Supplementary Material for: SPECKLE TRACKING ECHOCARDIOGRAPHY IN TWIN PREGNANCIES AND THE ROLE OF GLOBAL LONGITUDINAL STRAIN AND PEAK SYSTOLIC STRAIN: A SYSTEMATIC REVIEW AND META-... حسب Meireson E. (20224101)

"…The global longitudinal strain in the right and left ventricle and the peak systolic strain in the right ventricle of the recipient MCDA twin is significantly decreased compared to the donor MCDA twin. 2D STE assessment was shown feasible and reproducible in MCDA pregnancies. …"

Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx حسب Hanna Mebus (19961244)

"…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …"

NWB2024_A change of monograph publication patterns after the implementation of the Polish Publishers List حسب Emanuel Kulczycki (98040)

"…The number of monographs published by publishers not included in PPL significantly decreases while there is a noticeable upward trend in the publication of monographs with Level 2 publishers noted for their prestige and alignment with international standards. …"

A comprehensive assessment of sustainable mortar containing tannery sludge and wheat straw fibre حسب Rkia Zari (22698213)

"…The density and thermal conductivity of the mortars measured after 28 days decreased with the fibre content increased. Adding 6 wt.% WSF reduces the dry composite’s lighter by 15% and enhances its thermal insulation capacity by about 70%. …"