Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Thermodynamic properties of non-azeotropic refrigerant heat pumps under full operating conditions with non-phase-change heat sinks and heat soucres by Hemin Hu (21488860)

“…A comprehensive thermodynamic assessment = across all operating conditions indicated that <i>COP</i> of all configurations decreases markedly as heat production diminishes below 50% of full load. …”

Data - developmental timing. by Saeko Takada (21616085)

“…In this study, we examined the function of Trus during <i>Drosophila</i> development. CRISPR/Cas9 generated null mutations in <i>trus</i> lead to partial embryonic lethality, significant larval developmental delay, and complete pre-pupal lethality. …”

Table 7_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Data Sheet 2_Neuron-specific enolase in patients with acute and chronic schizophrenia, diversity of approaches: marker of neuronal death, neurodegeneration or neurodevelopmental th... by Alicja Sierakowska (21248987)

“…A tendency towards correlation between severity of negative symptoms of schizophrenia and decreased levels of NSE were observed. In addition, a trend was noted between an increase in NSE level and the severity of positive symptoms. …”

Table 5_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Table 3_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Table 8_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Improving genomic prediction for plant disease using environmental covariates by Charlotte Brault (22078544)

“…The predictive ability slightly decreased when the target environment was less related to the training environments. …”

Table 2_Elucidating the impact of organic amendments on soil bacterial communities and strawberry yield in North Carolina.xlsx by Tika B. Adhikari (9310247)

“…Our results from 16S microbiome amplicon sequencing showed significant variations in the composition of the soil bacterial community over time between the organic amendment treatments and the controls. …”

Table 6_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Table 2_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Table 4_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog... by Alia Albush (21669206)

“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”

Figure 7 from Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain by Stamatia C. Vorri (19563842)

“…<p>Single-chain proximal IL7Rα CAR-T cells have decreased <i>in vivo</i> antileukemia activity. <b>A,</b> Schematic of the xenograft model. …”

Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr... by Zemmar A. (11259339)

“…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …”

Supplementary Material for: How the COVID-19 Pandemic Impacted Neurological Hospital Admissions in Germany - A Retrospective Analysis by figshare admin karger (2628495)

“…While overall admissions decreased, average case severity was significantly higher. …”

Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus. by Md Rezaul Islam (19649494)

“…Red color denotes increased and blue color decreased expression in stimulated mice. …”

CRISPR/Cas9-mediated editing of barley lipoxygenase genes promotes grain fatty acid accumulation and storability by Zhanghui Zeng (3571331)

“…Notably, the total LOX activity in mature grains decreased by 36–42% in <i>loxC1</i> mutants and by 94% in <i>loxAloxC1</i> mutants, with no significant change observed in <i>loxB</i> mutants. …”

Low-speed Rear-end Collisions: Kinematic and Clinical Responses (Video, MRI findings, EMG/NCS results) by Hee Young Lee (22195417)

“…Pain questionnaires were administered immediately after the test and one week later.</i></p><p dir="ltr"><b><i>Results</i></b><i>: Impact velocity, offset percentage, and collision type significantly influenced acceleration forces and NIC values, with passenger vehicle collisions generating higher forces than bumper car collisions. …”