بدائل البحث:
significant i » significant _ (توسيع البحث), significant co (توسيع البحث), significant 17 (توسيع البحث)
side decrease » sizes decrease (توسيع البحث), fid decreased (توسيع البحث), we decrease (توسيع البحث)
step decrease » sizes decrease (توسيع البحث), teer decrease (توسيع البحث), we decrease (توسيع البحث)
i decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), _ decreased (توسيع البحث)
significant i » significant _ (توسيع البحث), significant co (توسيع البحث), significant 17 (توسيع البحث)
side decrease » sizes decrease (توسيع البحث), fid decreased (توسيع البحث), we decrease (توسيع البحث)
step decrease » sizes decrease (توسيع البحث), teer decrease (توسيع البحث), we decrease (توسيع البحث)
i decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), _ decreased (توسيع البحث)
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Juvenile demyelination impairs the maturation of PV interneurons in the PFC.
منشور في 2025"…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …"
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Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties.
منشور في 2025"…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …"
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Juvenile demyelination induces a loss of functional autapses.
منشور في 2025"…Cuprizone-treated mice show a significant decrease in the percentage of cells showing an autaptic response (<i>Fisher’s exact test; *p = 0.0173</i>). …"
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Autapses play a crucial role in PV interneuron’s sustained firing at high frequencies.
منشور في 2025"…Average action potential (AP) frequency in response to 0−650 pA current steps illustrating a significant increase in PV interneuron firing frequency at low-current steps in control cells without autapses (gray) compared to control cells with autapses (black). …"
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Comparison between juvenile and adult demyelination.
منشور في 2025"…Summary data showing the averaged (± s.e.m) of the following intrinsic properties: (A) Resting membrane potential (RMP) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: *p < 0.05, **p < 0.01, ****p < 0.0001</i>), (B) Input resistance (IR) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0024, post-hoc LSD test: *p < 0.05, **p < 0.01, ***p < 0.001</i>), (C) Sag (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0083, post-hoc LSD test: *p < 0.05, **p < 0.01</i>), (D) Rheobase (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, p = 0.1230, post-hoc LSD test: *p < 0.05</i>) and (E) Action potential (AP) threshold (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, *p = 0.0452, post-hoc LSD test: *p < 0.05</i>), (F) AP half-width (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0058, post-hoc LSD test: **p < 0.01</i>), (G) Average action potential (AP) frequency in response to 0–650 pA current steps illustrating no significant change in S1 PV interneuron firing frequency following juvenile demyelination (<i>group x current two-way repeated measures: n = 36,30,19,24 cells from 9/8/8/6 mice per group: F(39,1,291) = 2.487, ****p < 0.0001</i>) and (H) Maximum firing frequency per group (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: ***p < 0.001, ****p < 0.0001</i>). …"
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Comparison of questionnaire scores among genotypes for the significant associations.
منشور في 2025الموضوعات: -
316
NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission.
منشور في 2025"…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P < 0.001). …"
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Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the <i>OCT</i> Gene, which is Highly Expressed in the Spermathecal...
منشور في 2025"…Diallyl trisulfide (DAT) effectively inhibits the fecundity of Sitotroga cerealella. <i>Organic cation transporter</i> (<i>OCT</i>) was most highly expressed in the spermathecal gland of female moths and was significantly decreased after DAT fumigation. …"
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Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the <i>OCT</i> Gene, which is Highly Expressed in the Spermathecal...
منشور في 2025"…Diallyl trisulfide (DAT) effectively inhibits the fecundity of Sitotroga cerealella. <i>Organic cation transporter</i> (<i>OCT</i>) was most highly expressed in the spermathecal gland of female moths and was significantly decreased after DAT fumigation. …"