Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence by Huimin Chang (21142907)

“…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …”

Sustainable separation of Xe from the noble gas mixture of Ar, Kr, and Xe using cryogenic distillation and gas hydrates hybrid methods by Saeideh Babaee (16908064)

“…This hybrid separation method contributes to sustainability by significantly reducing energy consumption and operating costs, which in turn mitigates greenhouse gas emissions and decreases dependence on nonrenewable energy sources.…”

Anthropogenic CO2–induced seawater acidification driven the biogeochemical processes of dimethylsulfide in Northwestern Pacific marginal seas by Xuxu Gao (9724883)

“…Seawater acidification exerts significant control over marine biogeochemical cycles, including those involving of dimethylsulfide (DMS), a critical climate-regulating sulfur compound. …”

<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b> by Ge Qiao (21802511)

“…LOXL2 knockdown led to decreased tumor cell proliferation, enhanced apoptosis, and cell cycle arrest. …”

Supplementary Material for: A Case Report of Intravitreal Aflibercept for Iris Metastasis from Small Cell Lung Carcinoma with Neovascular Glaucoma by figshare admin karger (2628495)

“…Although not curative, this therapeutic approach may play a significant role in the symptom management of these patients.…”

Alterations in nasal airflow and air conditioning after endoscopic nasopharyngectomy for recurrent nasopharyngeal carcinoma: a pilot computational fluid dynamics study by Dong Dong (23216)

“…<p>Endoscopic nasopharyngectomy represents a significant intervention for recurrent nasopharyngeal carcinoma (NPC). …”

Enhanced Anthropogenic Contributions to Marine Aerosols and trace elements Compared to Coastal Regions in Northern China by Yang Zhou (17600586)

“…These results highlight significant interaction between sea salt and dust or anthropogenic elements, which may enhance the solubility of these trace elements. …”

Noninvasive neurally-adjusted ventilatory assist in preterm infants: a systematic review and meta-analysis by Yohei Minamitani (19853854)

“…There were no significant differences in secondary outcomes with low to very low certainty of evidence.…”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

The impact of controlled release fertilizer on the growth and physiology of advanced seedlings of sour passion fruit by Luanna Fernandes Pereira (8185335)

“…The 4–8 kg m⁻³ CRF dose resulted in a significant increase in seedling vigor 85 days after emergence stabilization. …”

<b>Community assembly mediate multitrophic biodiversity and soil multifunctionality relationships under climate warming and altered precipitation</b> by He Mao (20609462)

“…Furthermore, warming indirectly reduced the network complexity of multitrophic community by reducing the α-diversity of multitrophic community, and further decreased soil multifunctionality. The interaction between warming and precipitation changes had a significant effect on β multifunctionality. …”

Environmental changes and human activities influence the spatial patterns of plant diversity in Eastern Eurasian Steppe by Danyu Wang (12380464)

“…The Hulun Buir Steppe exhibits a natural environmental gradient with decreasing precipitation and temperature from east to west. …”

original data.xlsx by Peng Shen (20145351)

“…<b>Research Results</b>: The results showed that the levels of inflammatory factors significantly decreased in the blood purification treatment group after treatment, with a notable reduction in hospitalization and ICU stay duration compared to the conventional treatment group. …”

Divergent Oncogenic Signaling and Immune Microenvironment Changes in Low-Grade Serous Ovarian Cancer Undergoing Intraperitoneal Treatment by Isaac Bishara (21157583)

“…The non-responder demonstrated significant upregulation in proliferation-associated pathways (E2F, MYC targets, G2/M checkpoint), KRAS signaling, epithelial-mesenchymal transition, and unfolded protein response (UPR), correlating with aggressive tumor growth and treatment resistance. …”

Supplementary Material for: Effect of endobronchial valve treatment on skeletal muscles, fatigue, and sleep in severe emphysema patients by figshare admin karger (2628495)

“…Intercostal thickening fraction did not change following treatment. Fatigue decreased significantly, reducing severe fatigue prevalence from 70% to 25%. …”

<b>Effects of </b><b>agricultural land management and livestock grazing </b><b>intensification on ecosystem carbon and nutrient stocks</b> by Yuxi Guo (17400877)

“…Our results demonstrated that agricultural management intensification increased C, N, and P stocks in aboveground biomass and subsurface soil, while high-intensity grazing reduced nutrient stocks in vegetation. Significant interactive effects between management and grazing intensities showed in stoichiometric ratios: high-intensity grazing decreased C:P and N:P ratios in aboveground biomass, and C:N ratio in subsurface soil in SN pastures but increased these ratios in IM pastures. …”

<b>Evaluating Trauma-Focused Cognitive Behavioral Therapy in Earthquake Survivors: A Controlled Trial</b> by Metin Çınaroğlu (18498525)

“…<p dir="ltr">Traumatic events such as earthquakes often lead to significant psychological distress among survivors. …”

data.xlsx by Juanjuan cui (22072841)

“…During the development of nabkhas, foliar nitrogen and phosphorus decreased first and then increased, indicating that nutrient limitation changed from nitrogen to phosphorus, and microbial biomass C (MBC) and microbial biomass nitrogen (MBN) changed significantly, indicating that the scale of microbial community was constantly adjusted. …”

Image 2_Astragaloside IV alleviates GDM via regulating gut microbiota and gut microbiota metabolomic.tif by Fengge Wang (4347442)

“…</p>Results<p>After the 25-day intervention, the GDM model + AS IV group showed significantly decreased fasting blood glucose levels (p = 0.0003), mean insulin levels (p = 0.0001), and insulin resistance index (p = 0.0001). …”