Funnel plot shows the prevalence of HIV- related internalized stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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A funnel plot shows the distribution of HIV-related perceived stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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Sub-group analysis of HIV-related perceived stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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Egger’s test of HIV-related perceived stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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Extracted excel spreadsheet data of included studies on HIV-related perceived stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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Sub-group analysis of HIV-related internalized stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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Factors associated with HIV-related perceived stigma among people living with HIV/AIDS in Africa. حسب Gebresilassie Tadesse (18069820)

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Prediction of the effect of the 9 nsSNPs on AKT2 proteins’ structure and function by eight computational tools. حسب Sadia Afrin Runa (22504971)

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Distribution of SNPs and their frequencies based on mutation classes. حسب Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Capivasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Ipatasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Akt1/Akt2-IN-1 (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Predicted pathogenicity of R274H, Y265N, and R467W substitutions and their molecular mechanisms. حسب Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Akt1/Akt2-IN-1 through molecular dynamics simulations. حسب Sadia Afrin Runa (22504971)

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Non-covalent interactions between Capivasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Binding affinity of Akt1/Akt2-IN-1, Capivasertib, and Ipatasertib with AKT2 (wild and mutants) protein. حسب Sadia Afrin Runa (22504971)

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Superimposed structures of AKT2 native (green color) and mutant (red color) models to visualize the stereochemical conformation of wild type and mutant residues at (a) 274, (b) 265... حسب Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Ipatasertib complex through molecular dynamics simulations. حسب Sadia Afrin Runa (22504971)

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Non-covalent interactions between Ipatasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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