Genome-wide association analysis provides insights into the genomics and extracellular expression of <i>Staphylococcus aureus</i> proteases by Shuxian Li (20556455)

“…To identify the genetic variation underlying this variation in protease expression, we employed a <i>k</i>-mer-based genome wide association study, identifying 68 genes with polymorphisms significantly associated with proteolytic activity. Population-scale genomic variation was compared with strains from a sequenced- defined transposon library, validating the function of 27 loci that were significantly associated with decreased protease expression. …”

Image 2_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.jpeg by Xiaoyang Yuan (11216262)

“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”

Image 1_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.jpeg by Xiaoyang Yuan (11216262)

“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”

Data Sheet 1_The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation.docx by Qian Qian (45749)

“…Neutrophil-related markers like IL6, IL8, and neutrophil extracellular traps (NETs) were significantly elevated in this model. Inhibiting neutrophils production significantly improved airway inflammation and lung function. …”

Image 3_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.tif by Xiaoyang Yuan (11216262)

“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein by Xiangchao Jia (21392720)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx by Demet Kartal (20817926)

“…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …”

Datasheet1_Combined endovascular interventions for pulmonary embolism at high altitude in Tibet.zip by Tengyan Yang (19834944)

“…The heart rate (p < 0.05) and respiratory rate (p < 0.001) of all enrolled patients were significantly decreased, and the peripheral capillary oxygen saturation (SpO2) was significantly increased (p < 0.05) after interventions. …”

Algorithms for designing continuous curricula A: Decision tree showing the continuous version of ADP which includes actions that “grow” and “shrink” the increments between continuo... by William L. Tong (22238845)

“…<p>See the text for more details of the task in the continuous setting. B: ADP significantly outperforms INC when the task is difficult (low <i>ε</i>). …”

Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx by Jessica Alves Freitas (20974076)

“…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”

CDCP1 regulates CDA and hENT1 expression through c-Src/PKCδ signaling pathway. by Kun-Lin Hsieh (11401919)

“…T24-CD cells exhibited increased CDA and decreased hENT1 expression, whereas T24-CDKO cells showed the opposite trend. …”

Areal densities of single targets in the feeding areas of northern and southern resident killer whales. by Burak Saygili (19832062)

“…Prey densities differed significantly between feeding areas, and generally decreased as the fish migrated from west to east towards the Fraser River. …”

Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... by Yuanling Yang (22524785)

“…In contrast, 400 μM MT treatment effectively mitigated oxidative damage by coordinated activation of superoxide dismutase (SOD,+14.3%), peroxidase (POD,+21.7%), and catalase (CAT,+11.7%) activities, thereby stabilizing membrane integrity. Furthermore, MT significantly alleviated photoinhibition: F_V/F_M increased by 39%, Y_II and qP rose, and NPQ decreased compared to salt-stressed plants, reflecting enhanced protection of the PSII reaction center and optimized light energy allocation. …”

Raw data for figures and tables in the paper. by Runhai Jiang (19871068)

“…<i>rwandensis</i> could promote the transformation of Pb fractions and a functional change in the soil bacterial community, ultimately decreasing Pb accumulation in the biomass and promoting the development of maize.…”

Ictogenic changes in input correlation and adaptation gains are associated with increased dynamical variability during baseline activity. by Scott Rich (9873638)

“…<b>B</b>: <i>U</i>_<i>e</i> and <i>U</i>_<i>i</i> Normalized SD during baseline activity (top) and SLE rate (bottom) in the default model compared to two non-ictogenic scenarios— decreased from 50.0 to 40.0 and decreased from 1.2 to .8. …”

Data Sheet 1_Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage po... by Maolin Chu (11611507)

“…Furthermore, reducing cellular LXN/Rps3/p53 signaling significantly decreased SASP factors in the culture medium and simultaneously abolished M1-like phenotype macrophage polarization. …”

Method for establishing the multipath adaptive mitigation model considering deformation displacement of monitoring stations by Guo Zihuai (20442074)

“…The comparison between MAMM and the Multipath Hemispherical Model (MHM) indicates that, in the simulated displacement experiments, MHM’s effectiveness in mitigating multipath errors significantly decreases as the actual displacement distance increases, whereas MAMM consistently maintains an improvement rate in positioning precision of over 100%, markedly surpassing that of MHM. …”

Supplementary Material for: Metabolic analysis of three-dimensional cultured gastrointestinal cancer cells suggests that L-arginine inhibits tumor growth by affecting the urea cycl... by Tanaka E. (4127287)

“…In OE33, S phase cells (determined using BrdU) were significantly reduced. In a comprehensive metabolic analysis of OE33, citrulline/ornithine levels were significantly lower in arginine-treated than in untreated cells. …”

Image3_Effects of polystyrene microplastics on the growth and metabolism of highland barley seedlings based on LC-MS.png by Wenqi Xiao (17657980)

“…Metabolome analysis revealed that the contents of 4 metabolites increased significantly with increasing PS-MPs concentration in positive ionmode, while the contents of 8 metabolites increased significantly with increasing PS-MPs concentration in negative ionmode (P < 0.05), including prunin, dactylorhin E, and schisantherin B. …”

Image7_Effects of polystyrene microplastics on the growth and metabolism of highland barley seedlings based on LC-MS.png by Wenqi Xiao (17657980)

“…Metabolome analysis revealed that the contents of 4 metabolites increased significantly with increasing PS-MPs concentration in positive ionmode, while the contents of 8 metabolites increased significantly with increasing PS-MPs concentration in negative ionmode (P < 0.05), including prunin, dactylorhin E, and schisantherin B. …”