يعرض 19,681 - 19,700 نتائج من 21,342 نتيجة بحث عن '(( significant impact decrease ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.40s تنقيح النتائج
  1. 19681

    Data Sheet 1_Effect of NR1D1 on the proliferation and differentiation of yak skeletal muscle satellite cells.pdf حسب Yuqi Zhe (20107152)

    منشور في 2024
    "…Compared with those in the control group, the expression levels of proliferation marker genes KI-67, CYCLIND1, and CYCLINA were significantly inhibited after NR1D1 overexpression, which was also supported by the CCK-8 test, whereas differentiation marker genes MYOD, MYOG, and MYF5 were significantly inhibited. …"
  2. 19682

    Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx حسب Eryun Zhang (20172057)

    منشور في 2024
    "…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …"
  3. 19683

    Table 2_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

    منشور في 2025
    "…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"
  4. 19684

    Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model حسب figshare admin karger (2628495)

    منشور في 2025
    "…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …"
  5. 19685

    Global maximum GPP from 2001-2018 حسب Xu (7493744)

    منشور في 2025
    "…The GPPmax estimates from this study and the changes in their trends were highly correlated with GPPmax estimates from the vegetation photosynthesis model, with R2 > 0.70 for most vegetation types. The GPPmax significantly increased in western North America, northern Europe, and eastern China, but decreased in tropical regions. …"
  6. 19686

    Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf حسب Rong Wu (152554)

    منشور في 2025
    "…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…"
  7. 19687

    Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx حسب Feilong Yang (1472296)

    منشور في 2025
    "…In FaDu HSCC cells, siRNA-mediated HDGF knockdown significantly attenuated proliferation, migration, and invasion. …"
  8. 19688

    Table 2_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx حسب Junzhe Chen (5729912)

    منشور في 2025
    "…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …"
  9. 19689

    Table 1_Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.docx حسب Tuanjie Wang (6619406)

    منشور في 2025
    "…</p>Conclusion<p>Although the global burden of diarrhea has decreased significantly, it is still high in low-income countries and low- and medium-SDI areas, and newborns are at high risk. …"
  10. 19690

    Supplementary Material for: Comparing Two Oral Immunotherapy Strategies for Sesame Allergy: Baked Goods with Sesame Paste Versus Crushed Sesame Seeds حسب figshare admin karger (2628495)

    منشور في 2025
    "…For both the baked goods and the seeds group, likelihood of severe reactions significantly decreased over time. Conclusion: A modified sesame desensitization protocol using baked sesame paste can be safely used in children with sesame allergy.…"
  11. 19691

    Table 6_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx حسب Baixing Wei (21461966)

    منشور في 2025
    "…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …"
  12. 19692

    Data Sheet 1_The pan-cancer landscape of aldo-keto reductase1B10 reveals that its expression is diminished in gastric cancer.docx حسب Anqi Wu (3413069)

    منشور في 2024
    "…In tumor microenvironment, AKR1B10 was significantly correlated with immune cell infiltrations and immune gene expression. …"
  13. 19693

    Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif حسب Yaqi Cui (10798865)

    منشور في 2025
    "…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …"
  14. 19694

    Image 3_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... حسب Junhyeok Choi (14078586)

    منشور في 2025
    "…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"
  15. 19695

    Differences in lesion development of slow- and fast-growing meat-type chickens after experimental challenge with <i>Enterococcus cecorum</i> حسب Amanda Rosenbaum (19074302)

    منشور في 2025
    "…Extra-intestinal colonization with EC at 43/44 dph was significantly reduced in group ESG compared to EFG (<i>P</i> < 0.05). …"
  16. 19696

    Presentation_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.pdf حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  17. 19697

    Image 3_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif حسب Houle Guo (21264647)

    منشور في 2025
    "…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …"
  18. 19698

    Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis حسب Jianan Feng (11178007)

    منشور في 2025
    "…<p>Individuals with chronic kidney disease (CKD) exhibit a significantly elevated risk of premature mortality, predominantly attributable to cardiovascular etiologies. …"
  19. 19699

    Data Sheet 1_Herbal essential oils improve growth, antioxidant response, and gene expression in Nile Tilapia fingerlings.pdf حسب Malik Khalafalaa (22225135)

    منشور في 2025
    "…</p>Results and discussion<p>The 30 and 60 mL/kg groups showed significantly improved final body weight, weight gain, specific growth rate, and feed conversion ratio (p < 0.05). …"
  20. 19700

    Table 4_Gut microbiota alterations in golden snub-nosed monkeys during food shortage and parturition-nursing periods.doc حسب Guanwei Lan (14131365)

    منشور في 2025
    "…We found that in adult males, gut microbiota diversity significantly decreased in food shortages and parturition-nursing period. …"