Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…PTA decreased as CrCL increased, with slight variations observed across different PLT levels. …”

Table 1_The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990–2019 in China.docx by Yongyao Shen (20561210)

“…The EAPC of ASDR was found to be significantly negatively correlated with the 1990 ASDR (ρ = −0.393, p = 0.024), and the EAPC of ASMR and ASDR were also significantly negatively correlated with the 2019 SDI (ASMR:ρ = −0.571, p < 0.001; ASDR:ρ = −0.368, p = 0.035).…”

Table 1_The mitochondrial function of peripheral blood cells in cognitive frailty patients.docx by Li Qin (205731)

“…</p>Conclusion<p>Age, lower educational attainment, malnutrition, and depression are significant risk factors for CF. Moreover, mitochondrial dysfunction, characterized by decreased mtDNAcn, impaired respiratory function and increased ROS levels appears to be a critical phenotype of CF.…”

Image 3_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

“…Healthy control also showed globally increased [¹⁸F]SMBT-1 uptake. There was no significant correlation between the degree of [¹⁸F]FDOPA uptake and [¹⁸F]SMBT-1 uptake in any brain region.…”

Image 1_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.tif by Han-han He (20594477)

“…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …”

Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Image 1_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”

Table 1_The relationship between dietary sodium intake and all-cause mortality in patients with non-alcoholic fatty liver disease: a cohort study from NHANES 2003–2018.docx by Jiajun Li (1410187)

“…For intakes above this threshold, no significant relationship with mortality risk was observed (HR = 0.99, 95% CI = 0.90, 1.08).…”

Image 5_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”

Supplementary Material: Spent hemp biomass as a feed ingredient for beef steers: effects on performance, blood parameters, behavior, cannabinoid residues, and consumer exposure lev... by Agung Irawan (14145081)

“…However, the potential accumulation of cannabinoids in animal products, particularly the psychoactive compound ∆⁹-tetrahydrocannabinol (Δ⁹-THC), remains a significant barrier to the legalization of SHB as a feed ingredient for livestock. …”

Impact of mobility in a three-region system with heterogeneous epidemic conditions. by Mousumi Roy (8869412)

“…From left to right, we consider the scenarios with decreasing outgoing mobility and increasing non-commuting population. …”

Table 1_Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005–2020.docx by Chaoyue Mo (21684056)

“…Although these changes were statistically significant, their clinical relevance may vary depending on individual cardiovascular risk profiles.…”

Image 6_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”

Supplementary file 1_Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.doc by Yanli Hou (6561536)

“…When analyzed categorically, the ΔcAG still exhibited a significant risk gradient across quartiles.</p>Conclusion<p>Further elevated cAG after ICU admission demonstrates a robust association with an increased mortality risk in critically ill patients. …”

Table 2_The effect of Traumeel LT ad us. vet. on the perioperative inflammatory response after castration of stallions: a prospective, randomized, double-blinded study.docx by Julia Laves (19779357)

“…All stallions had the highest pain summary score 8 hours after surgery, with decreasing values thereafter. The pain scores were not statistically different at any time point. …”

Supplementary file 1_Negative associations between macronutrient quality index and lung cancer incidence and mortality: results from the prostate, lung, colorectal, and ovarian can... by Dazhan Feng (22286776)

“…Our results demonstrate a distinct, statistically significant inverse association between a higher MQI and both a reduced incidence (HR Q4 vs. …”

Numerical data and gene lists for all graphs. by Hilary T. Brewis (11798006)

“…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …”

Image 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif by Chanchan Xiao (9522614)

“…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”

Image 1_Cerebral small vessel disease as a possibly immune-related adverse event of immunotherapy in lung cancer patients: a retrospective study.tif by Na Wu (240778)

“…In the CSVD group, FT₄ levels decreased significantly between baseline and at the time of CSVD diagnosis, from 13.21 ± 4.56 pmol/L to 11.01 ± 2.11 pmol/L. …”