SLMO is required for the proper function of PISD. by Siwen Zhao (543384)

“…<p>(A) Schematic of the genome-wide RNAi screen for factors that prevent the rescue effects of PISD on the ERG defects of <i>pect</i>^<i>RNAi</i>. …”

Table 1_Belimumab-driven reductions in retinal microvascular density assessed by optical coherence tomography angiography: insights from systemic lupus erythematosus patients.docx by Maierhaba Maitiyaer (18947791)

“…Linear regression showed a significant negative association between Belimumab treatment and parafoveal DCP-VD. …”

Data Sheet 1_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf by Sunil Dhungel (21449354)

“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”

Table 1_Thiamine administration and in-hospital mortality in patients with traumatic brain injury: analysis of the MIMIC-IV database.docx by Shuangqi Gao (12729101)

“…In the subgroup analysis, the results demonstrated that thiamine administration resulted in a decreased risk of in-hospital mortality among TBI patients who aged 65 years or older (HR = 0.36, 95% CI: 0.19–0.69), as well as male individuals (HR = 0.36, 95% CI: 0.17–0.80) and those with severe TBI (HR = 0.16, 95% CI: 0.04–0.57).…”

Data Sheet 2_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf by Sunil Dhungel (21449354)

“…Attention scores also decreased at 800 meters (94.4%, p = 0.002). No significant changes were found in parietal, temporal, or occipital lobe functions. …”

Table1_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.docx by Eryun Zhang (20172057)

“…</p>Results<p>Differential expression analysis identified a total of 486 significantly changed transcripts. …”

Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…</p>Results<p>Differential expression analysis identified a total of 486 significantly changed transcripts. …”

Table4_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…</p>Results<p>Differential expression analysis identified a total of 486 significantly changed transcripts. …”

Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…</p>Results<p>Differential expression analysis identified a total of 486 significantly changed transcripts. …”

Divergent gene expression in <i>D. sechellia.</i> by Daehan Lee (5043377)

“…<p><b>(A)</b> Histogram of the frequency of <i>D. sechellia</i>-specific DEGs across 94 cell types, arranged by decreasing DEG number. …”

Data Sheet 1_The oncometabolite R-2-hydroxyglutarate inhibits microglial activation via the FTO/NF-κB pathway.docx by Lu Wang (45927)

“…</p>Discussion<p>Our findings reveal that R-2HG specifically inhibits microglial inflammatory activation by suppressing the FTO/NF-κB signaling pathway, leading to decreased IL-6 production. This study provides a novel mechanism by which R-2HG modulates the tumor immune microenvironment, which may be beneficial for exploring the basis of antitumor immunity in IDH-mutant gliomas.…”

Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…This suggests an underutilisation of available treatments, highlighting a gap in the management of high CV risk patients.…”

CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis by Baoping Deng (9081380)

“…</i> Our findings revealed a significant upregulation of circFNDC3B expression in AAA clinical specimens compared to normal tissues. …”

Supplementary file 1_ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels.pdf by Xuexue Liu (3271641)

“…Mechanistically, exposure to ZnO NPs did not significantly affect the IK1, but it markedly decreased I_Na and I_Ca−L currents, resulting in a reduced amplitude and shortened duration of the action potential in cardiomyocytes. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…Only two serious adverse events were reported (one hyperkalemia and one decreased white blood cell count).</p>Conclusion<p>This real-world study supports the effectiveness and safety of serplulimab-based regimens as a first-line treatment for patients with locally advanced or metastatic esophageal cancer, regardless of their diverse characteristics.…”

Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png by Yu Liu (6938)

“…Although temozolomidee has a certain efficacy in the treatment of brain malignancies, its numerous adverse effects (AEs) suggest that its safety needs to be thoroughly evaluated.…”

Effects of repeated intravenous esketamine administration on affective biases by Christine Reif-Leonhard (20516212)

“…Misclassifications of other emotions as sad also decreased (<i>p</i> = .035, d = −0.79), indicating a reduced response bias towards sadness. …”

Supplementary file 1_Roles of oral anticoagulant use on the risk of 28-day mortality and in-hospital mortality in patients with acute respiratory distress syndrome.docx by Jiayang Huang (17943998)

“…After adjusting for the respective confounding factors, the associations of Warfarin with decreased risk of 28-day and in-hospital mortality were not significant (P > 0.05).…”

Applications of Human Biostasis in Crewed Space Exploration by Josh Universe (21186797)

“…<p dir="ltr">Applications of Human Biostasis for Crewed Space Exploration is a presentation by Josh Universe, the Founder of the International Biohacking Community and Transhumanist Council, a science communicator, and a scientist-astronaut candidate. …”

Altered spatial distribution of EPDCs in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG hearts. by Andrew B. Harvey (21587431)

“…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …”