Data Sheet 1_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv by Ben Wang (250897)

“…However, among these genes, only S100A8 that was increased in ALI and decreased markedly after T0 treatment exhibited a negative correlation with T0. …”

Image 1_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.tif by Ben Wang (250897)

“…However, among these genes, only S100A8 that was increased in ALI and decreased markedly after T0 treatment exhibited a negative correlation with T0. …”

Image 2_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.tif by Ben Wang (250897)

“…However, among these genes, only S100A8 that was increased in ALI and decreased markedly after T0 treatment exhibited a negative correlation with T0. …”

Data Sheet 4_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv by Ben Wang (250897)

“…However, among these genes, only S100A8 that was increased in ALI and decreased markedly after T0 treatment exhibited a negative correlation with T0. …”

Data Sheet 3_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv by Ben Wang (250897)

“…However, among these genes, only S100A8 that was increased in ALI and decreased markedly after T0 treatment exhibited a negative correlation with T0. …”

Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”

Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx by Ningning Chen (509273)

“…Moreover, microRNAs (miRNAs) are an important class of gene expression regulators. We found that the upregulated hsa-miR-33a-5p repressed IGFBP5 translation by forming a silencing complex with Argonaute protein 2 (AGO2) in a real-ambient PM exposure system, which further led to the suppression of the ERK1/2-SOD2 signaling pathway and increased levels of ROS.…”

Original images for explaining Fig 4. by Reiri Takeuchi (20460788)

“…Treatment with cyclosporine A markedly increased cell proliferation, inhibited G₁ cell cycle arrest, significantly increased <i>CDC25A</i> and <i>CYCLIN E1</i> mRNA expression levels, significantly decreased <i>P21</i>, <i>SMAD3</i> and <i>SMAD4</i> mRNA expression levels, significantly upregulated the protein expression levels of CDC25A, CYCLIN E1, pCDK2 and pRB1 and significantly downregulated the protein expression levels of P21, SMAD3 and SMAD4. …”

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf by Mengyuan Dai (9747317)

“…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …”

Data Sheet 1_Alternate wetting and drying irrigation at tillering stage enhances the heat tolerance of rice by increasing sucrose and cytokinin content in panicles.docx by Ti Gao (21442307)

“…AWD increased the expression of CTK biosynthesis genes (IPT, CYP735A, LOG) and decreased that of CTK degradation gene CKX in roots and panicles under HDT, while enhanced the xylem sap flow rate and contents of CTKs, IAA, and GAs in panicles. …”

Data Sheet 1_Active layer and permafrost microbial community coalescence increases soil activity and diversity in mixed communities compared to permafrost alone.docx by Stacey J. Doherty (6629561)

“…Dispersal of microbial communities from the seasonally-thawed active layer soil into newly thawed permafrost may influence community assembly and increase carbon release from soils. We conducted a laboratory soil mixing study to understand how carbon utilization, heterotrophic respiration, and microbial community structure were affected when active layer and permafrost soils were mixed in varying proportions, as what is expected to occur when the terrain thaws. …”

TAD boundary stability for different noise amplitudes for all chromosomes. by Lucas Hedström (21688891)

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…To date, most OER catalyst discovery has relied on human-driven approaches that have led to an understanding of only a small proportion of all possible materials. In recent years, the advent of high-throughput virtual screening and machine learning has significantly increased the space that has been explored, but methods for experimentally validating the OER activities at scale are still limited and challenging. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…To date, most OER catalyst discovery has relied on human-driven approaches that have led to an understanding of only a small proportion of all possible materials. In recent years, the advent of high-throughput virtual screening and machine learning has significantly increased the space that has been explored, but methods for experimentally validating the OER activities at scale are still limited and challenging. …”

Data Sheet 1_Characterization of Ty21a immunostimulatory effects in the mouse bladder.pdf by Lenka Polak (17777406)

“…Indeed, CD8⁺ T-cell infiltration following Ty21a^FR was significantly decreased in TLR4- and MyD88-KO mice. …”

Table 2_Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review.xlsx by Tuerhongjiang Axirejiang (22346272)

“…Her serum zinc level significantly decreased (0.19 mg/L). Whole-exome sequencing revealed a homozygous c.197G > T(p. …”