Showing 13,181 - 13,200 results of 13,396 for search '(( significant increase decrease ) OR ( significant ((bit decrease) OR (point decrease)) ))*', query time: 0.69s Refine Results
  1. 13181
  2. 13182

    Table 3_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc by Md Shoykot Jahan (22776341)

    Published 2025
    “…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. …”
  3. 13183

    Combatting opioid misuse, overuse and abuse: a systematic review of pharmacists' services and outcomes by Bhuvan KC (11503540)

    Published 2025
    “…Outcomes assessment indicated harm reduction, improved safety, increased non-opioid analgesic use, decreased opioid consumption, and enhanced pain management.…”
  4. 13184

    Image 1_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

    Published 2025
    “…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
  5. 13185

    Image 5_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

    Published 2025
    “…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
  6. 13186

    Table 3_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

    Published 2025
    “…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
  7. 13187

    Utilization of lactate trajectory models for predicting acute kidney injury and mortality in patients with hyperlactatemia: insights across three independent cohorts by Yipeng Fang (14132676)

    Published 2025
    “…When compared with the Traj-3, Traj-2 was only significantly associated with the decreased risk of hospital mortality (OR 0.17, 95% CI 0.14–0.20, <i>p</i> < 0.001), but no with the likelihood of AKI development (OR 0.90, 95% CI 0.77–1.05, <i>p</i> = 0.172). …”
  8. 13188

    Image 2_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif by Yujuan Wu (2249857)

    Published 2025
    “…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”
  9. 13189

    Image4_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

    Published 2025
    “…It also alleviated inflammatory responses, including microglial activation and leukocyte infiltration, relieved the impairment of the brain blood barrier and edema, and reduced neuronal apoptosis, axonal loss, and demyelination induced by EAE. The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. …”
  10. 13190

    Image 2_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif by Yiping Cao (1229856)

    Published 2024
    “…Pharmacological activation of local PVT A<sub>2A</sub>R with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …”
  11. 13191

    Data Sheet 1_Spleen tyrosine kinase inhibition mitigates radiation-induced lung injury through anti-inflammatory effects and downregulation of p38 MAPK and p53.pdf by Guoxing Zhang (4994213)

    Published 2024
    “…Syk was highly expressed in irradiated lung tissue, and fostamatinib inhibited the level of Syk expression. Syk inhibitor significantly alleviated the radiation-induced lung injury and downregulated the increased expression of p38 MAPK, p53, IL-1β, and IL-6 in lung tissue at 2 weeks after radiation. …”
  12. 13192

    Data Sheet 1_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.csv by Ying Dong (41989)

    Published 2025
    “…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
  13. 13193

    Image1_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

    Published 2025
    “…It also alleviated inflammatory responses, including microglial activation and leukocyte infiltration, relieved the impairment of the brain blood barrier and edema, and reduced neuronal apoptosis, axonal loss, and demyelination induced by EAE. The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. …”
  14. 13194

    Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

    Published 2025
    “…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
  15. 13195

    Image 8_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

    Published 2025
    “…Among them, BIN2 and CAPN12 were linked to an increased risk, while genes such as CXXC5 and KLRD1 were associated with decreased risk. …”
  16. 13196

    Table 1_Factors influencing net ecosystem carbon change in cold-temperate coniferous forests of the Da Xing’an Mountains: analysis across developmental stages based on stand, struc... by Zirui Wang (8783819)

    Published 2025
    “…</p>Results<p>Our findings demonstrate that: (1) Net Ecosystem Carbon Change (NECC) is co-limited by stand characteristics, structural diversity, and environmental factors, with stand characteristics exerting the strongest influence, primarily via direct effects. (2) As stands develop, the impacts of structural diversity (effect increasing from 8.68% to 16.44%) and soil factors (from 8.80% to 10.30%) on productivity intensify. (3) In contrast, the influence of climate (decreasing from 30.40% to 17.67%) and terrain (from 14.55% to 6.28%) diminishes with advancing growth stages.…”
  17. 13197

    <b>Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor, </b><b><i>Bcl6</i></b> by Dudley H. McNitt (20208081)

    Published 2024
    “…T follicular helper (Tfh) cells are increased in type 1 diabetic individuals and alterations in Tfh-like cells in the peripheral blood predicted individual responses to abatacept. …”
  18. 13198

    Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

    Published 2025
    “…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
  19. 13199
  20. 13200

    Table 1_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx by Jianing Liu (140090)

    Published 2025
    “…Objective<p>Metabolic syndrome (MetS) is a global issue increasingly threatening human health and the quality of life. …”