يعرض 13,261 - 13,280 نتائج من 13,396 نتيجة بحث عن '(( significant increase decrease ) OR ( significant ((bit decrease) OR (point decrease)) ))', وقت الاستعلام: 0.56s تنقيح النتائج
  1. 13261

    Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx حسب Jingjing Chen (293564)

    منشور في 2025
    "…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…"
  2. 13262

    Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx حسب Wenjia Ge (22687361)

    منشور في 2025
    "…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…"
  3. 13263

    Image 1_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif حسب Meirong Feng (22089665)

    منشور في 2025
    "…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …"
  4. 13264

    Table 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.docx حسب Qiwang Mo (9091292)

    منشور في 2025
    "…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR<sub>PDI</sub> = 0.85; 95% CI: 0.80–0.90; pooled HR<sub>hPDI</sub> = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …"
  5. 13265
  6. 13266

    Table_1_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... حسب Huan Xiang (460100)

    منشور في 2024
    "…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…"
  7. 13267

    Table 7_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  8. 13268

    Data Sheet 1_Modified ZhuJing pill protects retinal pigment epithelium against oxidative stress-induced epithelial–mesenchymal transition through Nrf2-mediated Akt/GSK3β pathway.do... حسب Ning Yang (114965)

    منشور في 2025
    "…Notably, the EMT-suppressing effect of mZJP was significantly attenuated upon Nrf2 silencing, as evidenced by enhanced cell migration, decreased epithelial marker expression (E-cadherin), increased mesenchymal marker expression (vimentin and α-SMA), suppression of the Nrf2 pathway, and activation of the Akt/GSK3β pathway.…"
  9. 13269

    Image 4_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff حسب Priscila Silva (556743)

    منشور في 2025
    "…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"
  10. 13270

    Data Sheet 1_Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Nelumbo).zip حسب Jiaxin He (11256475)

    منشور في 2025
    "…</p>Results<p>It revealed that the broad petal variation of M512 was caused by a reduction in petal length while maintaining width, whereas the narrow petal phenotype of CSFY resulted from a combination of increased length and decreased width. The final petal shapes in both variants were primarily determined by the total number of cells along the petal’s longitudinal (length) and transverse (width) directions, rather than by cell size or shape. …"
  11. 13271

    Table_1_Biological characterization and in vitro fungicide screening of a new causal agent of walnut leaf spot in Guizhou Province, China.DOCX حسب Xianxi Ao (19822227)

    منشور في 2024
    "…The optimum temperature for mycelial growth of representative strain D. segeticola C27 was 20°C. Increasing the light period significantly decreased conidia production and conidia germination. …"
  12. 13272

    Table 2_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  13. 13273

    Image 2_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif حسب Meirong Feng (22089665)

    منشور في 2025
    "…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …"
  14. 13274

    Image_3_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... حسب Huan Xiang (460100)

    منشور في 2024
    "…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…"
  15. 13275

    CLIC1 accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells by inhibiting the Nrf2/HO-1 signalling pathway. حسب Jingtong Xiong (22272139)

    منشور في 2025
    "…(e) The LDH levels were increased after Nrf2/HO-1 inhibition and were significantly higher in the OGD/R+CLIC1 silencing+Nrf2/HO-1 inhibition group compared to the OGD/R+CLIC1 silencing group. …"
  16. 13276

    Table 3_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  17. 13277

    Protocol for our RNA-seq. حسب Sabih Rashid (5618807)

    منشور في 2025
    "…Top graphs depict genes increased in <i>daf-2; aak(0)</i> mutants compared to <i>daf-2</i> controls, while bottom graphs depict those genes that were decreased. …"
  18. 13278

    Supporting data for “<b>Human Lipocalin-2 Variants: Therapeutic Evaluations</b>” حسب Haoyun Li (9151469)

    منشور في 2024
    "…</p><p dir="ltr">Following a high-fat diet, our findings demonstrated that C87A levels were significantly elevated in cardiac and epididymal white adipose tissue (eWAT). …"
  19. 13279

    Image 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.tif حسب Haipeng Zhang (3413288)

    منشور في 2025
    "…The analysis of ssGSEA revealed notable immune dysregulation in AIS patients, characterized by increased neutrophil infiltration and decreased level of Th17, Th1, and TFH cells. …"
  20. 13280

    Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff حسب Priscila Silva (556743)

    منشور في 2025
    "…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"