DataSheet_3_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.pdf by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

Hormone-sensitive BCa cells (MCF-7) comprise 3 subpopulations, distinguished by ER-α46 expression levels. by John J. Kim (11191609)

“…Bottom: scatter plots show that TAM increases mean ER-α46 expression level (***p < 0.0001, **p< 0.005, n_neg = 38, n_TAM = 65). …”

Table_3_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.xlsx by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

Image_1_Skeletal Muscle Change During Neoadjuvant Therapy and Its Impact on Prognosis in Patients With Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.jpeg by Xin-Yi Xu (9380853)

“…</p>Conclusions<p>This systematic review and meta-analysis revealed that skeletal muscle decreased significantly during neoadjuvant therapy in patients with gastrointestinal cancers and skeletal muscle loss was strongly associated with worse overall survival. …”

DataSheet1_The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis.pdf by Zaiwei Song (11590222)

“…Two SNPs were statistically associated with the increased risk of HDMTX toxicity: MTHFR 677C>T and hepatotoxicity (dominant, OR=1.52, 95% CI=1.03-2.23; recessive, OR=1.68, 95% CI=1.10–2.55; allelic, OR=1.41, 95% CI=1.01–1.97), mucositis (dominant, OR=2.11, 95% CI=1.31–3.41; allelic, OR=1.91, 95% CI=1.28–2.85), and renal toxicity (recessive, OR=3.54, 95% CI=1.81–6.90; allelic, OR=1.89, 95% CI=1.18–3.02); ABCB1 3435C>T and hepatotoxicity (dominant, OR=3.80, 95% CI=1.68-8.61), whereas a tendency toward the decreased risk of HDMTX toxicity was present in three SNPs: TYMS 2R>3R and mucositis (dominant, OR=0.66, 95% CI=0.47–0.94); RFC1 80A>G and hepatotoxicity (recessive, OR=0.35, 95% CI=0.16–0.76); and MTHFR 1298A>C and renal toxicity (allelic, OR=0.41, 95% CI=0.18–0.97). …”

DataSheet3_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.ZIP by Qianqian Huang (1409008)

“…</p><p>Results: Administration of GPCRAC extracts significantly recovered scopolamine-induced cognitive impairment, as evidenced by the improved learning and memory ability, increased Ach content and ChAT activity, as well as decreased AchE activity in the hippocampus of mice. …”

Table_1_Preoperative plasma visfatin may have a dual effect on the occurrence of postoperative delirium.docx by Ning Kang (327210)

“…A J-shaped association was observed between preoperative plasma visfatin levels and POD. The risk of POD decreased within the lower visfatin concentration range up to 37.87 ng/ml, with a hazard ratio of 0.59 per 5 ng/ml [odds ratio (OR) = 0.59, 95% confidence interval (CI) = 0.37–0.95], but the risk increased above this concentration (P for non-linearity < 0.001, with a hazard ratio of 1.116 per 10 ng/ml; OR = 1.10, 95% CI = 1.02–1.23). …”

Table_4_A Novel Densovirus Isolated From the Asian Tiger Mosquito Displays Varied Pathogenicity Depending on Its Host Species.XLS by Jing Li (10611)

“…Sublethal effects analysis also showed that AalDV-7 infection significantly decreased pupation and emergence rates. …”

Table_1_Cropping systems and agricultural management strategies affect soil organic carbon dynamics in semi-arid regions.DOCX by Aram Gorooei (14324583)

“…The value of labile-C was decreased during summer cultivations and increased in the soil samples collected after winter cultivations. …”

A novel cystatin derived from <i>Trichinella spiralis</i> suppresses macrophage-mediated inflammatory responses by Porntida Kobpornchai (8655378)

“…The fractions that exhibited high immunomodulatory property by decreasing pro-inflammatory cytokines or increasing anti-inflammatory cytokines were identified by mass spectrometry. …”

Effect of <i>Nacα</i> knockdown (KD) using various GAL4 drivers on heart function and structure. by Analyne M. Schroeder (13961877)

“…<b>E,</b> Fractional Shortening is significantly decreased using both <i>tinHE</i>-GAL4 and <i>tinCΔ4</i>-GAL4 driver, while <i>Dot</i>-GAL4 had no effect. …”

DataSheet_9_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.pdf by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

Table_6_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.xlsx by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

DataSheet_1_Multi‑institutional development and validation of a nomogram to predict prognosis of early-onset gastric cancer patients.docx by Hongda Liu (6702581)

“…Univariate and multivariate analyses were conducted to test prognostic significances of clinicopathological factors in the training set. …”

DataSheet_4_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.pdf by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

Table_5_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.xlsx by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

Table_4_Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia.xlsx by Cristina Calviño (17004837)

“…This analysis showed that T cells from AML patients displayed a predominantly effector phenotype, with increased expression of activation (CD69 and HLA-DR) and exhaustion markers (PD1 and LAG3), in contrast to the enriched memory phenotype observed in healthy donors. …”

Table_1_Visuomotor Adaptation Brain Changes During a Spaceflight Analog With Elevated Carbon Dioxide (CO2): A Pilot Study.docx by Ana Paula Salazar (9745565)

“…During early adaptation across the HDBR+CO₂ intervention, participants showed decreasing activation in temporal and subcortical brain regions, followed by post- HDBR+CO₂ recovery. …”

Table_1_Sex-specific differences in immunogenomic features of response to immune checkpoint blockade.xlsx by Susan C. Scott (13191618)

“…In contrast, among males, there was no significant association between DCB and any of these features. …”

Knockdown of CRT suppressed VEGF-A expression and mRNA stability through ARE in AGS cells. by Po-Chu Lee (438366)

“…The remaining amount of VEGF-A mRNA in the CRT-knockdown cells was significantly decreased at 60 and 90 minutes compared to that in the control cells. …”