DataSheet1_Transcriptomic and sugar metabolic analysis reveals molecular mechanisms of peach gummosis in response to Neofusicoccum parvum infection.zip by Yang Zhang (30734)

“…Our results revealed that N. parvum infection drastically altered the transcripts of cell wall degradation-related genes, the log₂Fold change in the transcript level of Prupe.1G088900 encoding xyloglucan endotransglycosylase decreased 2.6-fold, while Prupe.6G075100 encoding expansin increased by 2.58-fold at 12 hpi under N. parvum stress. …”

Data Sheet 1_Morphological changes of lenticels and their role in gas exchange and sprouting physiology of potato tubers during postharvest storage.docx by Lembe S. Magwaza (18148945)

“…In both cultivars, distinct spatial differences were observed, with the apical section exhibiting a seven-fold increase in lenticel density compared to the lateral and stolon sections. …”

Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Table 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

“…Niraparib decreases CYP51A1 (lanosterol 14α-demethylase) enzyme levels (Supplementary Fig. …”

Multivariate statistical analysis diagram. by Ying Zhang (40767)

“…<p><b>(a, b)</b> PLS-DA diagrams. The separation pattern was satisfactory, with significant differences in principal components among the groups, indicating that the metabolic profiles underwent significant alterations between different groups. …”

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf by Wenjun Li (41954)

“…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …”

Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx by Chen-xiao Liu (22750118)

“…TCF3 knockdown significantly attenuated these EMT changes and increased autophagy markers, as evidenced by decreased P62 levels (p < 0.01) and increased LC3-II/I ratio (p < 0.001) and Beclin-1 expression (p < 0.01). …”

Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…However, transferring the spinner flask (SpF) process to the Ambr®250 STBr at constant P/V modified spheroid size, due to important geometric differences and impeller design. Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

<i>Tg</i>ATM1-depleted <i>Toxoplasma</i> are functionally complemented through expression of the <i>Plasmodium</i> or yeast homolog. by Deepti Shrivastava (17715780)

“…Unchanged proteins are displayed in black, while significantly altered proteins are displayed in grey (< 1.5-fold change (FC), local false discovery rate, LFDR < 0.05) or in blue (>1.5-fold increased; LFDR < 0.05) or red (> 1.5-fold decreased; LFDR < 0.05). …”

Downregulation of ATM1 affects iron-sulfur cluster proteins in <i>Toxoplasma</i> and iron levels in <i>Plasmodium</i>. by Deepti Shrivastava (17715780)

“…Unchanged proteins are displayed in black, while significantly altered proteins are displayed in grey (< 1.5-fold change (FC), local false discovery rate, LFDR < 0.05) or in blue (>1.5-fold increased; LFDR < 0.05) or red (> 1.5-fold decreased; LFDR < 0.05). …”

Supplementary file 1_Impacts of Bacillus-based biotics and an enzyme cocktail on growth performance, immunity, and gut pathogenic microorganisms of nursery pigs under commercial co... by Seong-Min Koo (21788807)

“…In terms of immunity, B treatment increased immunoglobulin M levels, while D treatment increased immunoglobulin A levels during weeks 0–2 (p < 0.01). …”

Study group background characteristics. by Zicheng Hu (3825313)

“…Minor, though not significant, increases were present in the <b><i>RxNFL+</i></b> group. …”

Figure 5 from Elraglusib Induces Cytotoxicity via Direct Microtubule Destabilization Independently of GSK3 Inhibition by Josh T. Coats (20321355)

“…Blots are representative of three independent experiments, and quantification combines three independent experiments. Fold change calculated vs. control, error bars represent SEM, and statistical significance was determined using one-way ANOVA, with <i>P</i> ≤ 0.05. ns, not significant; *, <i>P</i> < 0.05; ****, <i>P</i> < 0.0001.…”

Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx by Yanjing Zhang (401134)

“…Specifically, female patients had a 1.811-fold increased risk compared with male patients (OR = 1.811 [1.302, 2.519], p = 0.000), while patients with bipolar II disorder had a 1.695-fold increased risk compared with patients diagnosed with bipolar disorder (OR = 1.695 [1.320, 2.178], p = 0.000). …”