Showing 1,741 - 1,760 results of 13,329 for search '(( significant increase decrease ) OR ( significant ((greatest decrease) OR (small decrease)) ))', query time: 0.66s Refine Results
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    Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis by Tiantian Wang (1688881)

    Published 2025
    “…This study identified FHND5032, a novel small-molecule miR-124 inducer, as a potent therapeutic candidate for UC. …”
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    Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx by Juan Chen (61123)

    Published 2025
    “…</p>Conclusion<p>This study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. Furthermore, renal BDNF expression decreased locally, predominantly originating from proximal tubule cells, macrophages, and podocytes, possibly epigenetically inhibited by the upregulation of lnc RNA Bdnf-as.…”
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