يعرض 14,841 - 14,860 نتائج من 15,006 نتيجة بحث عن '(( significant increase decrease ) OR ( significant ((shape decrease) OR (we decrease)) ))', وقت الاستعلام: 0.59s تنقيح النتائج
  1. 14841

    Image 6_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg حسب Chenchao Zou (22768010)

    منشور في 2025
    "…</p>Results<p>GA treatment decreased PTGS2, lactate dehydrogenase, malondialdehyde, ferrous iron, ROS, and oxidized glutathione disulfide (GSSG) levels and increased cell viability, glutathione (GSH) levels, the GSH/GSSG ratio, and GPX4 protein levels in the injury models. …"
  2. 14842

    Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

    منشور في 2025
    "…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"
  3. 14843

    Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx حسب Makoto Takahashi (386772)

    منشور في 2025
    "…FW-D-fed fish also exhibited significantly increased muscle levels of unsaturated fatty acids, particularly docosahexaenoic acid (DHA), a nutrient beneficial for human health. …"
  4. 14844

    Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif حسب Yan Cheng (149222)

    منشور في 2025
    "…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …"
  5. 14845

    Table 2_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.docx حسب Yujuan Wu (2249857)

    منشور في 2025
    "…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …"
  6. 14846

    Supplementary file 2_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

    منشور في 2025
    "…Background<p>Blunt chest trauma, commonly caused by traffic accidents, falls, and violent incidents, results in both direct mechanical injury to the thoracic cavity—leading to increased intrathoracic pressure and vascular rupture—and indirect effects on the central nervous system (CNS), causing extensive damage that severely impacts patient health and quality of life. …"
  7. 14847

    Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development. حسب Daniel Sobrido-Cameán (5049743)

    منشور في 2025
    "…</i> 25°C control) leads to increased aCC NMJ terminal size and decreased postsynaptic GluRIIA, while not affecting subunit GluRIIB expression. …"
  8. 14848
  9. 14849

    Applications of Human Biostasis in Crewed Space Exploration حسب Josh Universe (21186797)

    منشور في 2025
    "…This reduction allows for smaller habitat designs, lighter spacecraft, and decreased fuel needs, ultimately reducing mission costs. …"
  10. 14850

    Data Sheet 1_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf حسب HyeMee Joo (175770)

    منشور في 2025
    "…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4<sup>+</sup> T cells with a reduction of CD4<sup>+</sup> T cell proliferation, while increasing the frequency of IL - 10-producing CD4<sup>+</sup> T cell responses. …"
  11. 14851

    Data Sheet 2_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf حسب HyeMee Joo (175770)

    منشور في 2025
    "…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4<sup>+</sup> T cells with a reduction of CD4<sup>+</sup> T cell proliferation, while increasing the frequency of IL - 10-producing CD4<sup>+</sup> T cell responses. …"
  12. 14852

    Validation of an abortive response with elevated NF-κB activity distinct from full lytic reactivation. حسب Elliott D. SoRelle (6527681)

    منشور في 2024
    "…(D) Frequencies of <i>CD38</i><sup>+</sup> and <i>BCL2A1</i><sup>+</sup> cells presented in 3C by treatment condition at 24 h and 48 h. Asterisks denote significantly decreased frequencies of <i>CD38</i><sup>+</sup> cells and increased frequencies of <i>BCL2A1</i><sup>+</sup> cells upon 4HT and 4HT+PAA treatment versus respective control treatments (n = 3 per condition; two-tailed Welch’s t-test; **p<0.01). …"
  13. 14853

    DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

    منشور في 2024
    "…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"
  14. 14854

    Muscles influence motoneuron at NMJ during the critical period, but motoneuron do not affect GluR composition in muscles. حسب Daniel Sobrido-Cameán (5049743)

    منشور في 2025
    "…<p><b>(A)</b> Heat stress experienced during the embryonic critical period (32°C vs. 25°C control) leads to decreased postsynaptic GluRIIA. Simultaneous genetic manipulation of aCC motoneuron during embryonic stages does not affect GluRIIA in muscles. …"
  15. 14855

    Data Sheet 1_Artificial intelligence–enhanced mapping of the international classification of functioning, disability and health via a mobile app: a randomized controlled trial.zip... حسب Zhandos Kurban (21985553)

    منشور في 2025
    "…Background<p>Mobile health applications and artificial intelligence (AI) are increasingly utilized to streamline clinical workflows and support functional assessment. …"
  16. 14856

    Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis حسب Shivam Kumar Pandey (22295532)

    منشور في 2025
    "…Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …"
  17. 14857

    Table 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.docx حسب Kexin Xu (757891)

    منشور في 2025
    "…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…"
  18. 14858

    Data Sheet 2_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip حسب Junhuang Zheng (21629486)

    منشور في 2025
    "…</p>Results<p>This meta-analysis included 11 studies. High LNR was significantly associated with decreased overall survival (OS) (multivariable HR=1.76, 95% CI=1.36-2.27; univariable HR=2.26, 95% CI=1.95-2.63) and increased risk of shorter disease-free survival (DFS) (multivariable HR=1.66, 95% CI=1.48-1.88). …"
  19. 14859

    Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx حسب Luana Pulvirenti (2925741)

    منشور في 2025
    "…As demand for year-round high-quality basil increases, alternative approaches that ensure consistent phytochemical profiles are needed. …"
  20. 14860

    Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx حسب Luana Pulvirenti (2925741)

    منشور في 2025
    "…As demand for year-round high-quality basil increases, alternative approaches that ensure consistent phytochemical profiles are needed. …"