P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). حسب Hong Yan Huang (20135965)

Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy حسب Ya-yin Tan (21448519)

"…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …"

DataSheet1_RETRACTED: Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn.DOCX حسب Kislay Roy (3466256)

"…</p><p>Methods: We investigated the synergistic regenerative potential of dominant negative survivin mutant (SurR9-C84A) and histone deacetylase (HDAC) inhibitor trichostatin-A (TSA) against alkali burn and corneal haze using human keratocytes and rabbit alkali burn model (Female New Zealand white rabbits).…"

Key safety measures including adverse events. حسب Anuja Dokras (8679261)

"…<div><p>Background</p><p>The risk-to-benefit ratio of using combined oral contraceptive pills (COCPs) and/or metformin for comprehensive management of polycystic ovary syndrome (PCOS) in women with obesity is unclear. As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.…"

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity حسب Mengyu Liu (2890397)

"…Herein, we exposed Neuro-2a cells to different concentrations of TMT (2, 4, and 8 μM) for 24 h. …"

Data Sheet 1_Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway.pdf حسب Zulipikaer Wusiman (20852138)

"…In addition, transcriptome analysis indicated that GA likely acts through the mitogen-activated protein kinase (MAPK) signaling pathway. GA has a strong binding affinity for important targets.GA significantly increased the expression of genes such as mapk8b, mapk14a, mapk3, mitf, tyr, tyrp1b, tyrp1a, dct, and oca2, and decreased the expression of genes such as expression of genes such as raf1 and egfr. …"

A typical cross signalized intersection. حسب Bin Zhao (276445)

"…Numerical experiments using actual survey data from Kunshan City yield several noteworthy findings: (1) An optimal moderate-sized time step exists for rolling optimization to minimize either the average delay time or total costs; specifically, an excessively small time step may increase vehicle average delay time or total costs; (2) The percentage of delay reduction achieved by our method, compared to Synchro software, reaches a maximum of approximately 70% when traffic demand is moderate and the initial state is low; and (3) The percentage reduction in average delay or total costs compared to Synchro initially increases and then decreases with rising traffic intensity.…"

Supporting datasets for all figures. حسب Matthew Drill (22258391)

"…Inhibition of P2X7R with small molecule antagonist AZ10606120, for 72 hours significantly decreased U251 cell number (p < 0.0001), and significantly increased tumour cell death, as evidenced by increased LDH release (p < 0.001). …"

Patients outcome. حسب Loïc Duron (6433634)

"…Reliance on temporal-artery biopsy fell (17% vs 91%; p < 0.01), owing to a four-fold rise in diagnostic MRI use. Mean total medical costs decreased by €814 per patient (€3672 ± 2861 vs €4486 ± 3193), although this difference did not reach statistical significance (p = 0.23).…"

CHAMPS pilot Hb dataset. حسب Jeanie du Toit (20721918)

"…Postmortem testing showed a significant decrease in hemoglobin concentrations compared to antemortem levels. …"

Raw data underlying the findings in this study. حسب Andrew Mvula (20161161)

"…The relative bone density significantly decreased as standard length and condition factor (<i>K</i>) increased in both sexes. …"

Predictors in ordinal regression model for GDS. حسب Shane Naidoo (20148021)

"…In an ordinal regression model BMI was a significant predictor (<i>B</i> = .10, <i>p</i> = .007) for increases in depression. …"

Classification of hand grip strength. حسب Shane Naidoo (20148021)

"…In an ordinal regression model BMI was a significant predictor (<i>B</i> = .10, <i>p</i> = .007) for increases in depression. …"

Rating scale for functional severity [28]. حسب Shane Naidoo (20148021)

"…In an ordinal regression model BMI was a significant predictor (<i>B</i> = .10, <i>p</i> = .007) for increases in depression. …"

Regression model coefficients. حسب Shane Naidoo (20148021)

"…In an ordinal regression model BMI was a significant predictor (<i>B</i> = .10, <i>p</i> = .007) for increases in depression. …"

ICOPE screening positive participant’s responses. حسب Shane Naidoo (20148021)

"…In an ordinal regression model BMI was a significant predictor (<i>B</i> = .10, <i>p</i> = .007) for increases in depression. …"

WHO BMI classification for adults. حسب Shane Naidoo (20148021)

"…In an ordinal regression model BMI was a significant predictor (<i>B</i> = .10, <i>p</i> = .007) for increases in depression. …"

Dataset. حسب Hao Wang (39217)

"…The findings reveal that minimum wage increases are significantly associated with a reduction in both strategic CSR and responsive CSR. …"

Moderating effect of CSR-sensitivity (RCSR). حسب Hao Wang (39217)

"…The findings reveal that minimum wage increases are significantly associated with a reduction in both strategic CSR and responsive CSR. …"

Moderating effect of CSR-sensitivity (SCSR). حسب Hao Wang (39217)

"…The findings reveal that minimum wage increases are significantly associated with a reduction in both strategic CSR and responsive CSR. …"