بدائل البحث:
significant processes » significant progress (توسيع البحث), significant promise (توسيع البحث), significant increases (توسيع البحث)
processes decrease » progressive decrease (توسيع البحث)
increase decrease » increased release (توسيع البحث), increased crash (توسيع البحث)
significant processes » significant progress (توسيع البحث), significant promise (توسيع البحث), significant increases (توسيع البحث)
processes decrease » progressive decrease (توسيع البحث)
increase decrease » increased release (توسيع البحث), increased crash (توسيع البحث)
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1501
Supplementary file 1_Altered microstate C and D dynamics in high social anxiety: a resting-state EEG study.docx
منشور في 2025"…</p>Results<p>The high social anxiety group exhibited significantly increased duration and coverage of microstate C (associated with processing personally significant information and self-reflection) and decreased duration and coverage of microstate D (associated with executive functioning). …"
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1502
<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b>
منشور في 2025"…The extent of RBCs’ retention was partially mitigated by blocking purinergic signaling, indicating a contribution of the HlyA-induced volume increase in this process.</p><p dir="ltr">Our results suggest that the increase in cytosolic Ca<sup>2+</sup> elicited by HlyA impacts RBCs’ circulation by decreasing RBCs’ deformability and increasing spleen retention. …"
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1503
hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor
منشور في 2025"…Significant increased level of <i>PI3K</i> (p < 0.0001), <i>AKT</i> (p < 0.0001), and UL823 (p < 0.0001) was observed in brain tumor patients compared to controls. …"
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1504
Data corresponding to the publication by Di Miceli, Rossitto, Martinat, Marchaland, Kharbouche, Graland, Younes, Séré, Aubert, Rabbaa Khabbaz, Madore, Delpech, Martín & Layé.
منشور في 2024"…At PND64, Csf1r, Tmem119 as well as C3ar1 were significantly increased in males born by C-section, but not in females. …"
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1505
Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
منشور في 2025"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"
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1506
Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx
منشور في 2025"…The results revealed that when the temperature dropped from 30°C to 0°C, the amylase activities and the content of maltose and glucose increased, while the starch content decreased. During the process, the up-regulation of LaAMY and LaBAM1/3 suggests an adaptive response in L. angustifolia to cold stress by promoting the breakdown of starch. …"
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1507
Data Sheet 1_Successional patterns of microbial communities across various stages of leaf litter decomposition in poplar plantations.pdf
منشور في 2025"…</p>Results<p>The microbial community structure and composition exhibited significant differences at both the class and genus levels throughout the entire decomposition process. …"
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1508
Molecular signatures underlying multisensory gamma stimulation-associated cognitive benefits in the hippocampus.
منشور في 2025"…Red color denotes increased and blue color decreased expression in stimulated mice. …"
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1509
Data Sheet 1_Effects of nitrogen application amount on nitrogen distribution and photosynthesis in tea leaves.pdf
منشور في 2025"…In the light capture system, the two varieties displayed different trends: FD’s nitrogen distribution decreased, while JF’s increased. Our results indicated that within a certain range, increasing nitrogen levels can significantly enhance the photosynthetic capacity of tea plants and improve photosynthetic nitrogen use efficiency. …"
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1510
DataSheet1_Case report: Comprehensive clinical, pathological and genetic investigations to decipher the background of cyclic thrombocytopenia.pdf
منشور في 2024"…The pathomechanism of the disease is poorly understood, several pathological processes have been implied in the background of CTP. …"
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1511
Dynamic Analysis of Membrane Emulsification: An In Situ Observation and Calculation with Deep Learning Model
منشور في 2025"…Using this device, we demonstrated that decreasing the pore size or increasing the dispersed phase flow rate induces droplet formation transition from dripping to jetting, with the Weber number (<i>We</i><sub>d</sub>) quantifying this critical condition (<i>We</i><sub>d</sub> = 16 ± 12%). …"
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1512
Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
منشور في 2025"…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
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1513
Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
منشور في 2025"…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
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1514
Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
منشور في 2025"…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …"
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1515
Table 1_Impact of hearing loss on brain signal variability in older adults under different auditory load conditions.docx
منشور في 2025"…In contrast, we found that hearing loss reduced brain signal variability during speech recognition tasks, especially in noisy conditions, in the mild hearing loss and moderate to severe hearing loss groups, possibly indicating decreased neural processing efficiency. Additionally, a positive correlation between brain signal variability and speech recognition performance was observed in healthy control participants across all SNR conditions, suggesting that brain signal variability could dynamically respond to the precise level of auditory environment demands. …"
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1516
Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
منشور في 2025"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"
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1517
Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf
منشور في 2025"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"
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1518
Data Sheet 1_Intratumoral and fecal microbiota reveals microbial markers associated with gastric carcinogenesis.docx
منشور في 2024"…Network analysis showed that the positive correlation with GC-enriched bacteria increased, and the positive correlation with GC-depleted bacteria decreased compared to healthy individuals. …"
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1519
Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
منشور في 2025"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"
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1520
Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
منشور في 2025"…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…"