Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx by Jikai He (11888466)

“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”

Data Sheet 1_Gram-positive enhancer matrix delivering FVpE via M cell targeting elicit protective mucosal and adaptive immune responses against Helicobacter pylori infection.doc by Furui Zhang (3181935)

“…Finally, H. pylori-infected mice treated with GEM-SAM-FVpE can significantly reduce the colonization of H. pylori in gastric tissue while also decreasing gastric mucosal damage.…”

Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx by Jikai He (11888466)

“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”

Table_2_Factors influencing human papillomavirus vaccine uptake among parents and teachers of schoolgirls in Saudi Arabia: a cross-sectional study.DOCX by Deema I. Fallatah (19855410)

“…The attitude score significantly increased by high knowledge score and decreased if the person has previously diagnosed with cervical cancer.…”

Supplementary file 1_Identifying early blood glucose trajectories in sepsis linked to distinct long-term outcomes: a K-means clustering study with external validation.docx by Huan Ma (713125)

“…Conversely, patients with a “high-stable” trajectory (HR: 1.61, 95% CI: 1.35-1.92, P < 0.001) and those exhibiting unstable trends had significantly higher mortality risks (“high-decreasing”, HR: 1.38, 95% CI: 1.16-1.65, P < 0.001; “moderate-increasing”, HR: 1.37, 95% CI: 1.18-1.60, P < 0.001). …”

Table_1_Factors influencing human papillomavirus vaccine uptake among parents and teachers of schoolgirls in Saudi Arabia: a cross-sectional study.DOCX by Deema I. Fallatah (19855410)

“…The attitude score significantly increased by high knowledge score and decreased if the person has previously diagnosed with cervical cancer.…”

Table_1_Factors influencing human papillomavirus vaccine uptake among parents and teachers of schoolgirls in Saudi Arabia: a cross-sectional study.DOCX by Deema I. Fallatah (19855410)

“…The attitude score significantly increased by high knowledge score and decreased if the person has previously diagnosed with cervical cancer.…”

Table_2_Factors influencing human papillomavirus vaccine uptake among parents and teachers of schoolgirls in Saudi Arabia: a cross-sectional study.DOCX by Deema I. Fallatah (19855410)

“…The attitude score significantly increased by high knowledge score and decreased if the person has previously diagnosed with cervical cancer.…”

MCT4/CD147 transporter complex-associated cell proliferation, migration and invasion in U87 and U251 cell lines. by Chen Gao (159491)

“…The curves constructed from independent experiments revealed decreased cell proliferation in MCT4 and CD147 siRNA interference cells, but increased cell proliferation in lentivirus-transduced cells. …”

C2f and BC2f module structure diagrams. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx by Demos Kynigopoulos (12420457)

“…</p>Results<p>Alirocumab significantly improved spatial working memory, restored hippocampal long-term potentiation, and normalized synaptophysin expression. …”

Table 1_Exogenous myo-inositol enhances drought tolerance in maize seedlings by antioxidant defense, and photosynthetic efficiency.docx by Yuqi Liu (501183)

“…</p>Results<p>The results demonstrate that MI significantly restored growth parameters under drought conditions, increasing shoot and root biomass by 40.74% and 28.30%, respectively, on Day 7. …”

Image 10_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Image 3_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Image 3_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

YOLOv8n detection results diagram. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”

Image 1_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Image 7_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif by Chen Wang (88408)

“…Functional studies demonstrated that RBM15 loss led to increased expression of fumarate hydratase (FH). This led to decreased levels of fumarate, a metabolite known to suppress anti-tumor immune responses. …”

Table 1_Correlation between changes of amino acid spectrum and alopecia in patients with obesity undergoing bariatric surgery: a prospective cohort study.docx by Tingwen Wang (3927815)

“…</p>Results<p>Among 67 patients analyzed, LSG significantly decreased serum concentrations of arginine, alanine, threonine, glutamic acid, branched-chain amino acids (valine, isoleucine, leucine), and aromatic amino acids (tyrosine, phenylalanine, tryptophan) (p < 0.05), while serine and glycine increased (p < 0.05). …”

YOLOv8n-BWG model structure diagram. by Yaojun Zhang (389482)

“…Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”