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20161
Data Sheet 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.pdf
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
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20162
Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
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20163
Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…However, its limited ability to resolve cellular heterogeneity – particularly in samples containing residual non-tumor pituitary cells – remains a significant challenge.</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”
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20164
Table 4_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential...
Published 2025“…However, a consistent spatial pattern in nematode abundance was observed within all the seep areas on the Hikurangi Margin: abundance was highest at or near the seep centre, decreased steeply away from the centre and was low in the periphery. …”
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20165
Table 3_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential...
Published 2025“…However, a consistent spatial pattern in nematode abundance was observed within all the seep areas on the Hikurangi Margin: abundance was highest at or near the seep centre, decreased steeply away from the centre and was low in the periphery. …”
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20166
Table 2_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential...
Published 2025“…However, a consistent spatial pattern in nematode abundance was observed within all the seep areas on the Hikurangi Margin: abundance was highest at or near the seep centre, decreased steeply away from the centre and was low in the periphery. …”
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20167
Baseline characteristics of the study population.
Published 2025“…<div><p>Background</p><p>Intravenous immunoglobulin is a replacement therapy for patients living with primary immunodeficiencies. …”
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20168
Data Sheet 2_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20169
Data Sheet 6_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20170
Patient disposition.
Published 2025“…<div><p>Background</p><p>Intravenous immunoglobulin is a replacement therapy for patients living with primary immunodeficiencies. …”
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20171
Data Sheet 4_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20172
Data Sheet 5_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20173
Data Sheet 3_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. …”
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20174
Table_2_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX
Published 2025“…We found that bioclimatic zone had a significant effect on the gut microbiota composition while host phylogeny did not. …”
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20175
Data Sheet 3_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…Background<p>Laryngeal cancer poses a significant health burden among older adults, with varying incidence, mortality, and disability-adjusted life years (DALYs) across regions. …”
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20176
Data Sheet 4_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…Background<p>Laryngeal cancer poses a significant health burden among older adults, with varying incidence, mortality, and disability-adjusted life years (DALYs) across regions. …”
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20177
Data Sheet 5_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…Background<p>Laryngeal cancer poses a significant health burden among older adults, with varying incidence, mortality, and disability-adjusted life years (DALYs) across regions. …”
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20178
Data Sheet 2_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…Background<p>Laryngeal cancer poses a significant health burden among older adults, with varying incidence, mortality, and disability-adjusted life years (DALYs) across regions. …”
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20179
Data Sheet 6_Age-period-cohort analysis of global, regional, and national trends in laryngeal Cancer among older adults, 1990–2021: insights from the 2021 global burden of disease...
Published 2025“…Background<p>Laryngeal cancer poses a significant health burden among older adults, with varying incidence, mortality, and disability-adjusted life years (DALYs) across regions. …”
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20180
Image 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”