Table 7_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Image_2_Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018.TIFF by Yue Kang (427523)

“…A trend toward a decreasing prevalence of lung function indicators such as FEV1 [OR (95%CI), −339.70 (−456.53, −222.87)], FVC [OR (95%CI), −296.70 (−435.34, −158.06)], FEV1/FVC [OR (95%CI), −0.03 (−0.04, −0.02)], predicted FEV1 [OR (95%CI), −0.09 (−0.14, −0.04)], and predicted FVC [OR (95%CI), −0.08 (−0.15, −0.01)] was observed with increased NPS levels. …”

Graphical Abstract. by Furkan Özdemir (21560297)

“…Peak VO₂ (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”

PONE-Dataset. by Furkan Özdemir (21560297)

“…Peak VO₂ (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”

Demographic characteristics of groups. by Furkan Özdemir (21560297)

“…Peak VO₂ (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Mechanistically, TFA activated autophagy through the inhibition of PI3K/AKT/mTOR phosphorylation, as demonstrated by the increased LC3II/I conversion and decreased p62 expression. …”

Data_Sheet_2_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Table_2_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Table_3_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Image 2_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif by Wei Liu (20030)

“…In vitro, KSG mitigated Aβ_25-35-induced cytotoxicity in PC12 cells, decreased Aβ accumulation, and downregulated the expression of TNF-α and IL-1β. …”

Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Figure 2 from Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers by Maxim Kuznetsov (20201548)

“…<b>C,</b> Dependence of minimal single curative dose, <i>A</i>_<i>cur</i>, on relative significance of self-damage, <i>k</i>_<i>s</i>. …”

Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome by Yokoyama T. (4606381)

“…Kidney tissue sections from five patients with HPS-1 and one patient with HPS-6 were examined. Results Records from 205 adults and 52 children with HPS were reviewed. …”

Table2_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).xlsx by Xiaofei Xu (109890)

“…The cell wall disassembly-related genes PcPME3, PcPG1, PcPG2, PcPL, PcARF2, and PcGAL1, as well as ABA biosynthesis-related genes PcNCED1 and PcNCED2, were also significantly induced by ABA. …”