Showing 621 - 640 results of 19,593 for search '(( significant increase decrease ) OR ( significantly ((larger decrease) OR (a decrease)) ))', query time: 0.62s Refine Results
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    Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx by Juan Chen (61123)

    Published 2025
    “…</p>Conclusion<p>This study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. Furthermore, renal BDNF expression decreased locally, predominantly originating from proximal tubule cells, macrophages, and podocytes, possibly epigenetically inhibited by the upregulation of lnc RNA Bdnf-as.…”
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    Causal relationships between allergic diseases and significant declines in lung function: a multivariable Mendelian randomization study by Jiannan Lin (6954983)

    Published 2025
    “…However, in multivariable MR analysis, the independent effects of atopic dermatitis and allergic conjunctivitis on lung function were no longer significant. Only allergic asthma continued to show a significant causal relationship with decreased lung function (OR [95%CI]: 1.019 [1.008–1.030], <i>p</i> < .001).…”
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