Variance of the first 20 principal components from the essential dynamics analysis of the unbiased MD simulation of GumK in the membrane-bound state. by Davide Luciano (22822210)

“…The cumulative variance shows that the first few principal components account for a significant percentage of the total variance.…”

Enhanced Anthropogenic Contributions to Marine Aerosols and trace elements Compared to Coastal Regions in Northern China by Yang Zhou (17600586)

“…<p dir="ltr"><a href="" target="_blank">Terrestrial aerosols,</a> transported by westerly winds from Asian continent, continuously deliver both natural and anthropogenic nutrients to downstream marine ecosystems. …”

Data Sheet 1_Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease.docx by Xian Liu (191882)

“…The results indicated that Ru/Cur nanodots effectively eliminated various ROS and demonstrated significant therapeutic effects and biocompatibility in IR-AKI mice, reducing markers of kidney function damage, alleviating renal oxidative stress, and decreasing inflammatory cell infiltration. …”

DataSheet1_Strict biennial lifecycle and anthropogenic interventions affect temporal genetic differentiation in the endangered endemic plant, Pedicularis hallaisanensis.docx by Seongjun Kim (1993465)

“…Other cluster analyses also showed that a microhabitat under historical anthropogenic interventions contained lowered genetic diversity due to a decreased genetic distance between odd-year and even-year flowering cohorts (p < 0.05). …”

Raw data_(Submission ID 247694791) by Shengan Zhu (18242155)

“…<p dir="ltr"><a href="" target="_blank"><b>Background:</b></a> Reactive oxygen species (ROS), synthesized by the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) complex, are vital molecules in biological cells, influencing various physiological processes such as fungal growth, development, and virulence. …”

Supplementary file 1_Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation.docx by Joël Illi (21449474)

“…In the second step, varying the orientation of the structures had a significant influence on the elastic modulus, which was measured. …”

Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…(right): Self-renewal capacity of RD and AD-RD cells assessed by a sphere formation assay (n = 4). Statistical significance: ****p < 0.0001. c (top): Immunoblots from in vitro kinase assays treated with hit compounds and with EGFR inhibitors. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Additional file 2 of Evobrutinib mitigates neuroinflammation after ischemic stroke by targeting M1 microglial polarization via the TLR4/Myd88/NF-κB pathway by Yixiang Jiang (2580220)

“…Statistical analysis revealed no significant differences in CD80+ expression between MCAO and Evobrutinib group while the expression of MHCII+ microglia decreased in Evobrutinib group compared to MCAO. …”

PTEN KD induces EMT in epithelial CRC cells. by Ahmed H. Ghobashi (12705573)

“…EZH2i treated EV and PTEN KD cells act as a control for decreased H3K27me3 levels. <b>(C)</b> H3K27me3 band quantification for untreated EV and PTEN KD in HT29 and LS174T cells in (B). …”

Figure 2 from Loss of Sorting Nexin 10 Accelerates KRAS-Induced Pancreatic Tumorigenesis by Kohinoor Khan (22206206)

“…<p>OE of SNX10 decreased cell proliferation in AsPC1 and HPAF-II PDAC cell lines. …”

Data Sheet 1_The vicious circle: how systemic barriers perpetuate maternity interpreting service inadequacies for migrant women in the UK.docx by Li Li (14993)

“…</p>Results<p>The analysis revealed three interconnected systemic barriers forming a vicious circle in interpreting service provision: (1) Constrained user agency, where migrant women prioritised basic access to any interpreting support over preferences for service quality due to systematic service failures; (2) interpreter workforce sustainability crisis, with nearly 60.4% of interpreters having decreased or stopped healthcare interpreting assignments due to poor remuneration and better opportunities elsewhere; (3) infrastructure implementation failures, with interpreter-on-wheels implementation hampered by unreliable infrastructure, achieving only 11% utilisation despite its potential benefits.…”

<b>Precursor and Mature miRNA Sequences from the Hepatopancreas of Macrobrachium rosenbergii under Low-Temperature Stress</b> by jinlin gong (21467675)

“…The prawns were housed in a 4 m² indoor tank, where water temperature was gradually decreased from 26 °C to 0 °C at a rate of approximately 1 °C every 4 hours by incremental addition of ice. …”

Neural lamella remodeling is needed for macrophage invasion. by Bente Winkler (20760273)

“…Upon a panglial <i>Pvf2</i> expression macrophages invade the central nervous system more abundantly in later pupal stages compared to a panglial immunity induction. …”

DataSheet1_Neuroprotective effect of Bouvardia ternifolia (Cav.) Schltdl via inhibition of TLR4/NF-κB, caspase-3/Bax/Bcl-2 pathways in ischemia/reperfusion injury in rats.PDF by Yury Maritza Zapata-Lopera (19725616)

“…Introduction<p>Bouvardia ternifolia is a plant known for its traditional medicinal uses, particularly in treating inflammation and oxidative stress. …”

Table 1_Improved medical protective clothing comfort for medical staff facing high-intensity infectious diseases.docx by Cheng-teng Jiang (22028945)

“…A total of 208 volunteers participated in the experiment, yielding 196 valid data points (81 males and 115 females).…”

Sound evoked cortical activity across vigilance states before and after NOE. by Linus Milinski (10532121)

“…<p>(<b>A</b>) Experimental paradigm. Sounds were presented through a single loudspeaker located at the top of the enclosure over a period of 24 hours subsequent to 24 hours of undisturbed recordings. …”