Data Sheet 3_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 1_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 6_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Data Sheet 7_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip حسب Ziqin Wei (19433134)

"…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …"

Mitigating toxicity of arsenic in sunflower (<i>Helianthus annuus</i> L.) with phosphate rock and farmyard manure using contrasting soil textures حسب Muhammad Awais Piracha (21234904)

"…Plants were treated with As (60 and 120 mg kg⁻¹ soil), PR (5 and 20 g kg⁻¹ soil) and FYM (5 and 20% w/w) with a control. After sixteen weeks of growth period, results showed that As solubility decreased by 22.07–44.85% and 21.33–36.35% in sand, 17.55-45.80% and 30.83-45.98% in loam, while 22.81-36.89% and 20.92-42.41% in clay soils at As<b>-</b>60 and As<b>-</b>120, respectively with varied PR+FYM combinations compared to control. …"

Data Sheet 1_Peers are as persuasive as experts in reducing willingness to pay for sugary foods.pdf حسب Nina Arzumanyan (22759610)

"…</p>Results<p>All audio interventions significantly decreased participants’ WTP for sugar-containing products compared to sugar-free products. …"

The global disability-adjusted life years (DALYs) for asthma attributable to nitrogen dioxide pollution from 1990 to 2021 and predicted the trends from 2022 to 2050 حسب Yaping Feng (427666)

"…However, there may be a future rising tendency. Additionally, it is still quite significant for children under the age of 15 and in some underdeveloped regions.…"

CLIC1 accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells by inhibiting the Nrf2/HO-1 signalling pathway. حسب Jingtong Xiong (22272139)

"…(e) The LDH levels were increased after Nrf2/HO-1 inhibition and were significantly higher in the OGD/R+CLIC1 silencing+Nrf2/HO-1 inhibition group compared to the OGD/R+CLIC1 silencing group. …"

Descriptive Statistics. حسب Sayed Jubair Bin Hossain (22430672)

"…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…"

The result of the Negative Binomial Regression. حسب Sayed Jubair Bin Hossain (22430672)

"…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…"

Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX حسب Shaoqun Huang (19810725)

"…</p>Conclusion<p>Our study explored a significant correlation between PHDI and biological aging, indicating that adherence to PHD may prevent biological aging.…"

Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx حسب Qingguo Liu (9620123)

"…</p>Conclusions<p>Despite a decline in ASDR, the absolute burden of stroke attributable to metabolic risks among young adults has increased globally, with significant regional and national disparities. …"

Table 1_Pingwei Powder alleviates high-fat diet-induced colonic inflammation by modulating microbial metabolites SCFAs.xlsx حسب Tangjuan Liu (2634649)

"…Experimental validation showed that PWP significantly downregulated the levels of PI3K, pAKT/AKT, and pmTOR/mTOR in colonic tissue, thereby enhancing autophagy in colonic epithelial cells, as evidenced by decreased levels of P62 and increased LC3B-II/LC3B-I ratios. …"

Data of all figures حسب Bingqing Ye (5149703)

"…<p dir="ltr">Sepsis, a life-threatening organ dysfunction caused by dysregulated host responses to infection, often leads to sepsis-associated acute lung injury (SALI), a major contributor to mortality. …"

Table 4_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xls حسب Guilin Ren (18720749)

"…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …"

Table 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.xlsx حسب Xiao-Ting Luo (20836646)

"…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…"

Image 2_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg حسب Xiao-Ting Luo (20836646)

"…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…"

Data Sheet 1_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.doc حسب Guilin Ren (18720749)

"…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …"

Table 2_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx حسب Guilin Ren (18720749)

"…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …"

Table 7_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx حسب Guilin Ren (18720749)

"…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …"