DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Muscles influence motoneuron at NMJ during the critical period, but motoneuron do not affect GluR composition in muscles. حسب Daniel Sobrido-Cameán (5049743)

"…<p><b>(A)</b> Heat stress experienced during the embryonic critical period (32°C vs. 25°C control) leads to decreased postsynaptic GluRIIA. Simultaneous genetic manipulation of aCC motoneuron during embryonic stages does not affect GluRIIA in muscles. …"

Data Sheet 1_Artificial intelligence–enhanced mapping of the international classification of functioning, disability and health via a mobile app: a randomized controlled trial.zip... حسب Zhandos Kurban (21985553)

"…Background<p>Mobile health applications and artificial intelligence (AI) are increasingly utilized to streamline clinical workflows and support functional assessment. …"

Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis حسب Shivam Kumar Pandey (22295532)

"…Furthermore, LPS and FeSO₄ significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …"

Table 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.docx حسب Kexin Xu (757891)

"…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…"

Data Sheet 2_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip حسب Junhuang Zheng (21629486)

"…</p>Results<p>This meta-analysis included 11 studies. High LNR was significantly associated with decreased overall survival (OS) (multivariable HR=1.76, 95% CI=1.36-2.27; univariable HR=2.26, 95% CI=1.95-2.63) and increased risk of shorter disease-free survival (DFS) (multivariable HR=1.66, 95% CI=1.48-1.88). …"

Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx حسب Luana Pulvirenti (2925741)

"…As demand for year-round high-quality basil increases, alternative approaches that ensure consistent phytochemical profiles are needed. …"

Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx حسب Luana Pulvirenti (2925741)

"…As demand for year-round high-quality basil increases, alternative approaches that ensure consistent phytochemical profiles are needed. …"

Table 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc حسب Md Shoykot Jahan (22776341)

"…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. …"

Data Sheet 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.pdf حسب Yan Fan (575147)

"…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …"

Table1_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.DOCX حسب Wen Zhou (49050)

"…It also alleviated inflammatory responses, including microglial activation and leukocyte infiltration, relieved the impairment of the brain blood barrier and edema, and reduced neuronal apoptosis, axonal loss, and demyelination induced by EAE. The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. …"

Table 4_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc حسب Md Shoykot Jahan (22776341)

"…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. …"

Data Sheet 1_Evaluation of Lactiplantibacillus plantarum CRS 33 to therapeutic effects on a murine model of Escherichia coli-induced endometritis.zip حسب Mingchao Liu (1390666)

"…It also decreased pro-inflammatory cytokine levels and inflammatory cell infiltration, while enhancing microbial diversity and increasing the abundance of beneficial bacterial taxa.…"

Supplementary file 1_tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2.doc حسب Hui Li (32376)

"…</p>Results<p>NPC cells exhibited tRF-1:28-Val-CAC-2 upregulation that was associated with significantly increased proliferative, migratory, and invasive activity together with the suppression of apoptotic death. …"

Data Sheet 1_Changes in the prevalence of hepatitis B virus and its related factors in Inner Mongolia between 2006 and 2020.doc حسب Xuejie Ding (6634538)

"…By 2020, these proportions increased to 97.43 and 96.97%, respectively.</p>Conclusion<p>The prevalence of HBsAg decreased significantly from 2006 to 2020 in Inner Mongolia, suggesting that the Hep B vaccine has made remarkable progress in safeguarding the population against hepatitis B infection.…"

Supplementary file 1_Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omic... حسب Rui Hou (161624)

"…Multi-omics analyses revealed that GCT rapidly enriched beneficial taxa like Akkermansia and suppresses Firmicutes since the seventh day of intervention, leading to increased neuroprotective short-chain fatty acids (e.g., β-hydroxybutyrate) and decreased pro-inflammatory long-chain fatty acids in both serum and brain. …"

Plants components in five-flower remedy [24]. حسب Walaiporn Plirat (17775628)

"…The results revealed that the ethanolic extract of FFR alone improved outcomes in ECM, while its combination with artesunate significantly reduced parasitemia levels (80%), increased survival rates, reduced neurological deficits, and mitigated brain inflammation and behavioral changes. …"

Supplementary file 2_tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2.doc حسب Hui Li (32376)

"…</p>Results<p>NPC cells exhibited tRF-1:28-Val-CAC-2 upregulation that was associated with significantly increased proliferative, migratory, and invasive activity together with the suppression of apoptotic death. …"

Image8_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

"…It also alleviated inflammatory responses, including microglial activation and leukocyte infiltration, relieved the impairment of the brain blood barrier and edema, and reduced neuronal apoptosis, axonal loss, and demyelination induced by EAE. The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. …"

Image10_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

"…It also alleviated inflammatory responses, including microglial activation and leukocyte infiltration, relieved the impairment of the brain blood barrier and edema, and reduced neuronal apoptosis, axonal loss, and demyelination induced by EAE. The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. …"