Data_Sheet_2_Global, regional, and national burden and attributable risk factors of neurological disorders: The Global Burden of Disease study 1990–2019.xlsx by Chenyu Ding (8203221)

“…From 1990 to 2019, the DALYs of neurological diseases belonging to the communicable, maternal, neonatal and nutritional categories showed a sharp decrease, while Alzheimer's disease and other dementias and Parkinson's disease showed a large increase. …”

Image1_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg by Jiayu Ding (12005975)

“…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …”

Data_Sheet_1_Wave Climate Associated With Changing Water Level and Ice Cover in Lake Michigan.pdf by Chenfu Huang (11660707)

“…Model simulations suggest that the basin-wide H_s can increase significantly during the winter season with projected regional warming and associated decreases in winter ice cover. …”

Data Sheet 1_Comparative effectiveness and safety of sodium-glucose cotransporter 2 inhibitors vs glucagon-like peptide 1 receptor agonists in elderly patients with type 2 diabetes... by Yao Wang (102387)

“…</p>Conclusion<p>In conclusion, although SGLT2i increase the risk of EKA and GUI and GLP-1RA decrease the risk of AKI, SGLT2i are at comparable risk of MACE, HHF, MI, stroke, hypoglycemia, and fracture to GLP-1RA.…”

Table_2_Association between arteriosclerosis, hemodynamic indices, and the risk of falls: receiver operating characteristic curve analysis for different indices in older individual... by Kexin Zhang (301752)

“…Ordinal logistic regression analysis indicated that the probability of an increase in fall risk by one level was 2.069 times higher for each unit decrease in educational background. …”

PLK2i treatment of OHSCs does not affect generation of pS129 positive aggregates, but reduces the nuclear pS129 intensity. by Sara Elfarrash (8159490)

“…Scale bars = 20 μm. b) Quantification of the amount of aggregation (aggregate area normalized to tissue area), defined by MJF-14 staining (p-value = 0.09). c-d) Quantification of the mean fluorescence intensity of α-syn aggregates detected with MJF-14 (c, p-value = 0.712) and aggregate-specific pS129 that overlaps with MJF-14 (d, p-value = 0.214). e) Quantification of nuclear (non-aggregate related) pS129, illustrating a significant decrease in mean fluorescence intensity following PLK2i-treatment (p-value = 0.0087). f) Relative ratio of aggregate-specific pS129/nuclear pS129 in PFF-injected slices shows an increase of ratio of the signals of aggregates/background following PLK2i treatment, due to reduction of the non-aggregate-related nuclear pS129-signal (p-value = 0.009). …”

Table1_Synthesis and evaluation of gold nanoparticles conjugated with five antigenic peptides derived from the spike protein of SARS-CoV-2 for vaccine development.pdf by Susan Farfán-Castro (17891996)

“…The immunogenicity of the conjugates produced was assessed in test mice subjected to three subcutaneous doses at 2-week intervals. Significant levels of IgM against each target peptide were observed at an early stage of the immunization scheme in all groups, reaching maximum levels after the second dose, whereas the IgG response increased after the third dose. …”

ATP homeostasis is maintained by AMPK-FOXO-CKB pathway in HEK293 cells under oxidative stress conditions. by Nan Zhang (46264)

“…<b>(b)</b> Knockdown of <i>CKB</i> or <i>AMPKα1</i>/<i>α2</i> mRNA expression increased the fold of ATP decrease caused by paraquat treatment for 24h in HEK293 cells. …”

Image2_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg by Jiayu Ding (12005975)

“…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …”

Data_Sheet_1_Dietary Soluble and Insoluble Fiber With or Without Enzymes Altered the Intestinal Microbiota in Weaned Pigs Challenged With Enterotoxigenic E. coli F18.docx by Qingyun Li (845696)

“…The ETEC challenge reduced total volatile fatty acid (VFA) compared with NC (P < 0.05). The SF+ tended to increase (P < 0.10) and SF- significantly increased (P < 0.05) colonic total VFA compared with PC. …”

Data_Sheet_1_Telemedicine in Low- and Middle-Income Countries During the COVID-19 Pandemic: A Scoping Review.docx by Kareem Mahmoud (12904142)

“…</p>Conclusion<p>Telemedicine was found to improve access to high-quality healthcare and decrease infection risk in LMICs during COVID-19. In general, infrastructure and regulatory barriers found to be the most significant barriers to wider telemedicine use, and should be considered when implementing telemedicine more broadly. …”

DataSheet_1_Obesity paradox and aging: Visceral Adiposity Index and all-cause mortality in older individuals: A prospective cohort study.doc by Lei Wang (6656)

“…The restricted cubic spline model demonstrated a robust J-shaped link between VAI and all-cause mortality, revealing a significant decrease in risk within the lower range of VAI, which attained the lowest risk close to 1.7. …”

Data Sheet 1_DYRK1A roles in human neural progenitors.docx by Jeremie Courraud (20871932)

“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.…”

Table 4_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.docx by Zhicong Wang (810566)

“…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …”

Table1_The effect of 60 days of 6° head-down-tilt bed rest on circulating adropin, irisin, retinol binding protein-4 (RBP4) and individual metabolic responses in young, healthy mal... by Kiera Ward (9534059)

“…The subanalysis identified that in a subgroup with decreased whole-body insulin sensitivity (n = 17), RBP4 increased significantly, whereas adropin, irisin, and liver insulin sensitivity were all decreased significantly following HDT bed rest. …”

Table_1_Rational medication management mode and its implementation effect for the elderly with multimorbidity: A prospective cohort study in China.DOCX by Qi Tang (351973)

“…</p>Conclusion<p>The Rational Medication Management Mode based family physician service, which provides the support of manuals and pillboxes, can decrease the elderly patients' number of drugs with multimorbidity, reduce the incidence of polypharmacy, enhance behavioral self-management, increase the knowledge and belief of rational medication use, and improve the security and compliance of medication usage behavior. …”

Image_7_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Table_1_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.xls by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”

Pathogenic species of infection. by Chang Gao (5455919)

“…Ischemia time (OR 1.31, 95% CI 1.13–1.53, P = 0.001), wound contamination (OR 6.01, 95% CI 2.38–15.19, P <0.001), and stress hyperglycemia (OR 23.37, 95% CI 2.30–236.93, P = 0.008) were independent risk factors, while the albumin level after surgery (OR 0.94, 95% CI 0.89–0.99, P = 0.031) was significant associated with the decrease of postoperative wound infection. …”

Image_8_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIFF by Zhixing Kuang (10809975)

“…Background<p>Cachexia is defined as an involuntary decrease in body weight, which can increase the risk of death in cancer patients and reduce the quality of life. …”