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321
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
منشور في 2018"…</p><h3>Results</h3><p dir="ltr">Intrastriatal injection of α-syn PFFs to rats resulted in widespread accumulation of phosphorylated α-syn inclusions in several areas that innervate the striatum followed by significant loss (~ 35%) of substantia nigra pars compacta dopamine neurons within 5–6 months. …"
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322
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…The time required to develop bridging and subsequent clogging of the pore space that lead to permeability reduction decreases as the flow velocity increases. The size of the fine particles has a significant impact on permeability reduction where the reduction in permeability increases as the size of particles increases. …"
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323
Biochemical Characterization of Halotolerant Bacillus safensis PM22 and Its Potential to Enhance Growth of Maize under Salinity Stress
منشور في 2022"…Additionally, inoculation of the halotolerant bacteria PM22 reduced the severity of salinity stress in plants and increased root and shoot length at various salt concentrations (0, 180, 240, and 300 mM). …"
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324
Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report
منشور في 2018"…The NY-ESO-1-specific T cells response of the patient was found to be increased after the third and the fifth (**p = 0.002) cycles of treatment but had a significant decline after progression (**p = 0.0028). …"
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325
Trends in Necrotizing Fasciitis‐Associated Mortality in the United States 2003–2020: A CDC WONDER Database Population‐Based Study
منشور في 2025"…Additionally, urban–rural analysis indicated that large central metropolitan areas had consistently elevated mortality rates, whereas smaller metropolitan and noncore areas experienced sharper increases.</p><h3>Conclusions</h3><p dir="ltr">NF‐related mortality has significantly risen in the United States since 2014, with distinct disparities based on sex, race, and geographic region. …"
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326
Impact of COVID‑19 pandemic restrictions and subsequent relaxation on the prevalence of respiratory virus hospitalizations in children
منشور في 2024"…RSV infection rate dropped significantly during the COVID-19 season to 10.4% and then increased again during the post-COVID-19 season to 29.1% (<i>P</i> < 0.001). …"
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327
Voluntary disclosure of intellectual assets and intellectual liabilities
منشور في 2012"…The economical shift into knowledge and information management can explain the increased importance of intellectual capital as a research and business topic. …"
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328
Towards secure and trusted AI in healthcare: A systematic review of emerging innovations and ethical challenges
منشور في 2025"…Explainable AI (XAI) emerged as one of the significant developments. It made it possible for healthcare professionals to understand AI-driven recommendations, by this means increasing transparency and trust. …"
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329
Microbiome‐modulating nutraceuticals ameliorate dyslipidemia in type 2 diabetes: A systematic review, meta‐analysis, and meta‐regression of clinical trials
منشور في 2023"…However, widespread inter‐study heterogeneity and the presence of several unknown confounders limit their adoption in clinical practice; future trials should be designed with these in mind.…"
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330
Pharmacist-led educational interventions provided to healthcare providers to reduce medication errors: A systematic review and meta-analysis
منشور في 2023"…They are widespread in healthcare systems and are linked to an increased risk of morbidity and mortality. Several strategies have been studied to reduce their occurrence including different types of pharmacy-based interventions. …"
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331
Improving the performance of a commercial absorption cooling system by using ejector: A theoretical study
منشور في 2023"…<p>Absorption cooling systems (ACS) have lower coefficients of performance (COP) compared to direct expansion (DX) cooling systems. …"
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332
The association between tobacco use and COVID-19 in Qatar
منشور في 2022"…Smokeless tobacco use, older age (aged 55 + ), being male, non-Qatari, previously diagnosed with heart disease and diabetes were significant risk factors for severe COVID-19. Our data suggests that only smokeless tobacco users may be at an increased risk for severe disease, yet this requires further investigation as other studies have reported smoking to be associated with an increased risk of greater disease severity.…"
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333
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
منشور في 2024"…Expression of CaM<sup>D132E</sup> and CaMD134H mutants results in significant reduction of the zebrafish heart rate, mimicking a severe form of human bradycardia, whereas expression of CaM<sup>Q136P</sup> results in an increased heart rate mimicking human ventricular tachycardia. …"
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334
TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
منشور في 2019"…At low frequencies, the SOI and SELBOX showed comparable dynamic power dissipation but with lower values than the BULK structure. The difference in power dissipation between the SELBOX and BULK is in the order of nano watts. …"
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335
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. Qatar’s free access to cancer care represents a considerable economic burden. …"
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336
Pravastatin plus L-arginine prevents adverse pregnancy outcomes in women with uteroplacental vascular dysfunction
منشور في 2021"…</p><h3>Results</h3><p dir="ltr">PRAV+L-arginine improved uteroplacental haemodynamics, increased fetal growth and prevented early onset preeclampsia leading to delivery close to term (delivery date: median 38 weeks, IQR[36.5–39]) and appropriate weight for gestational age compared to controls, in which placental blood flow did not improve and 2 women developed severe early onset preeclampsia. …"
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337
Inflammatory Markers and COVID-19 Disease Progression
منشور في 2023"…</p> <h3>Conclusions</h3> <p>The data suggest a significant association between levels of inflammatory markers and COVID-19 severity. …"
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338
Information Technology Disaster Recovery Plan (IT DRP) Framework – A study on IT Continuity for Smart City in Abu Dhabi Smart Government
منشور في 2017"…Over the years, technology application in various fields of business has increased, with one such concept been seen in the form of smart cities. …"
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339
The Efficacy of Lubiprostone in Patients of Constipation: An Updated Systematic Review and Meta‐Analysis
منشور في 2025"…<h3>Background and Aim</h3><p dir="ltr">Lubiprostone increases chloride and water secretion in the intestines, and several studies have demonstrated the efficacy of lubiprostone in treating functional constipation. …"
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340
Predictors of malnutrition among older residents in Qatari long-term care facilities: a retrospective study
منشور في 2024"…Statistically significant predictors of mortality were malnutrition (OR 24.84, CI 1.09–564) and age (OR 1.07, CI 1.00–1.14).…"