Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …"

Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells حسب Sara Al Tamimi (9692615)

"…Furthermore, we observed the cell death pathway by the apoptosis marker Annexin-V which showed non-significant results, while the exposure of AgCu-NP in MCF-7 cells leads to toxicity and also caused significant increase in MMP-9 level, which suggests the cell death may be associated with other pathways such as autophagy and oxidative stress related.…"

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …"

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …"

A Multidecadal Assessment of Drought Intensification in the Middle East and North Africa: The Role of Global Warming and Rainfall Deficit حسب Ahmed El Kenawy (7510103)

"…For example, in comparison to the SPI, the SPEI indicated an increase of 15% in the areas affected by severe to very extreme droughts in arid regions (Aw). …"

Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19 حسب Matli, Kamal

"…Background COVID-19 is a respiratory disease that results in a prothrombotic state manifesting as thrombotic, microthrombotic and thromboembolic events. As a result, several antithrombotic modalities have been implicated in the treatment of this disease. …"
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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesen... حسب Lubna Therachiyil (4246156)

"…Our results showed that activation of AhR by TCDD in A2780 cells induced the PI3K/AKT pathway followed by induction of anti-apoptotic proteins BCL-2, BCL-xl, and MCL-1. In addition, a significant increase in stemness marker aldehyde dehydrogenase (ALDH1) was observed. …"

Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends حسب Isra E. Gilani (17019066)

"…<p dir="ltr">Desalination brine discharge has several negative impacts on the marine environment, such as increase in salinity levels, effects on marine biodiversity, and alteration of the physical and chemical characteristics of water. …"

Turkronicles: diachronic resources for the fast evolving Turkish language حسب Togay Yazar (22828175)

"…Our analysis reveals that the vocabulary has changed significantly and multiple spellings exist for several words. …"

Advanced Technology in Agriculture Industry by Implementing Image Annotation Technique and Deep Learning Approach: A Review حسب Normaisharah Mamat (19517623)

"…<p dir="ltr">The implementation of intelligent technology in agriculture is seriously investigated as a way to increase agriculture production while reducing the amount of human labor. …"

Effect of Diverse Seismic Hazard Estimates on Performance and Overall Cost of RC Shear Wall Buildings in Dubai, UAE حسب Aly, Nader Essam

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Deep aging clocks: AI-powered strategies for biological age estimation حسب Luma Srour (22254409)

"…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …"

Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study حسب Safna Nishad (16932474)

"…However, for hydrophobic colloids, changes in solution chemistry significantly increase colloid retention where the colloid interaction become attractive with the increase in ionic strength and decrease in pH values. …"

Implementation of corporate governance rules and procedures in lebanese firms حسب Elgammal, Walid

"…Corporate governance is composed of several elements performing specific functions. The main elements are: audit committee, external auditor, internal audit, and board of directors. …"
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Road deaths and injuries in India: Action required on the five pillars of road safety حسب Gopalakrishna Gururaj (19807233)

"…The economic losses from road crashes are estimated to be 3% of GDP and are increasing from year to year (2). Amidst significant regional variations, many Indian states have road deaths much above the national average. …"

The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study... حسب Nasser M Rizk (18810328)

"…The increase of Treg cells postoperative is significantly lower compared to lean subjects, p < 0.05. …"

Hygienic quality of chlorinated city water stored in household tanks in Byblos, Lebanon. (c2004) حسب Abi Chedid, Najib

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The impact of COVID-19 pandemic social restrictions on individuals with autism spectrum disorder and their caregivers in the Stateof Qatar: A cross-sectional study حسب Yasser Saeed Khan (17191735)

"…Out of these, 24 (41 %) reported a clinically significant increase in their care burden. Among caregivers reporting an increase in care burden, two-third were caring for individuals whose behaviour either remained unchanged or improved during social restrictions. …"

A Fully Optical Laser Based System for Damage Detection and Localization in Rail Tracks Using Ultrasonic Rayleigh Waves: A Numerical and Experimental Study حسب Masurkar, Faeez

"…First, the noise and unwanted wave packets increase with the increase in the time window and the inspection length. …"
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches حسب ALHAJERI, RASHED ABDULLA

"…Periodic based automatic cleaning showed decreases in improvement of between 164.64% to 245.34%. …"
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