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LSPC treatment decreases neuropathology in prion-infected mice.
Published 2019“…<p>Immunohistochemistry (IHC) of brain sections through the (A) cerebellum and (B) hippocampus in infected and uninfected mice reveal that (A) while we observed no difference in cerebellar PrP<sup>Res</sup> accumulation among infected untreated, non-responder or responder mice, both GFAP stain intensity, a measure of astrogliosis, and vacuolation, a hallmark of prion-mediated neurodegeneration, were significantly decreased in LSPC responder mice. …”
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Image_1_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF
Published 2020“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”
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Image_5_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF
Published 2020“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”
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Image_3_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.tif
Published 2020“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”
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Image_6_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF
Published 2020“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”
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Image_2_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF
Published 2020“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”
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Image_4_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.tif
Published 2020“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”
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K2 treatment increases access of a hydrophobic probe to the bacterial membrane of <i>K</i>. <i>pneumoniae</i>.
Published 2022“…</b> Three chemical analogs of K2 (dT = deoxythymidine, dU = deoxyuridine and 5-EdU = 5-Ethynyl-2’-deoxyuridine) were tested for their ability to increase the membrane accessibility of NPN. K2 was the only compound that increased significantly the accessibility of the outer membrane of <i>K</i>. …”
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Significantly Enriched Pathways.
Published 2025“…Pathway analysis revealed a marked decrease in expression within certain key metabolic pathways (such as the one-carbon pool by folate) in the NAFLD group, while expression in DNA repair-related pathways (such as non-homologous end joining) was significantly increased. …”
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Decreased Incidence of Type 1 Diabetes in Young Finnish Children
Published 2020“…In the middle age group, a significant decrease was observed only among females. …”