Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation by Larissa Haertle (3864310)

“…</p><h3>Materials and Methods</h3><p dir="ltr">A genome-wide DNA methylation study was performed using Illumina Infinium® MethylationEPIC BeadChips on whole blood DNA of 3 male T21 patients with low IQ, 8 T21 patients with high IQ (4 males and 4 females), and 21 age- and sex-matched control samples (12 males and 9 females) in order to determine whether DNA methylation alterations could help explain variation in cognitive impairment between individuals with T21. In view of the increased risk of developing AD in T21 individuals, we additionally investigated the T21-associated sites in published blood DNA methylation data from the AgeCoDe cohort (German study on Ageing, Cognition, and Dementia). …”

Renin–angiotensin-system gene polymorphisms and depression by Saab, Yolande B.

“…None of the other common RAS-associated polymorphisms were significantly associated. The results support the hypothesis that increased RAS activity may increase relative risk of depression in that the angiotensin receptor type 1 (A1166C) CC genotype is associated with increased responsiveness to angiotensin II.…”
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SGLT-2 inhibitors associated euglycemic and hyperglycemic DKA in a multicentric cohort by Fateen Ata (12217764)

“…Infection was the only risk factor with a significant point estimate between the two groups, being more common in hDKA patients (p-value 0.006, RR 2.53, 95% CI 1.07–5.98). …”

The predictive value of CTSI scoring system in non-operative management of patients with splenic blunt trauma: The experience of a level 1 trauma center by Ali Barah (14777533)

“…However, CTSI grade 3 is considered an increased risk of NOM failure, and further investigations are necessary to standardize its management.…”

Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

Effect of community-based intervention on knowledge and practice of rural mothers toward children home injuries by Marwa Mamdouh Shaban (18000123)

“…The mean total knowledge score increased from 39 ± 5.4 in the pretest to 41 ± 9.0 in the posttest, while the mean total practice score increased from 31.2 ± 5.7 in the pretest to 48.6 ± 9.7 in the posttest. …”

The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity by Robert Gharios (21393863)

“…Furthermore, the findings indicated that leverage had a significant negative impact on profitability. Finally, both the size and GDP have a significant beneficial impact on profitability. …”

Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response? by Darren J. Paul (6905450)

“…<p dir="ltr">Elevated postprandial triglyceride (TG) is associated with increased risk of cardiovascular disease. The time window for the last bout beneficial effect on postprandial lipaemia after football play is unknown. …”

Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials by Pieter Francsois, Fouche

“…Study objectiveTraumatic injury causes a significant number of deaths due to bleeding. Tranexamic acid (TXA), an antifibrinolytic agent, can reduce bleeding in traumatic injuries and potentially enhance outcomes. …”
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats by Daher, Costantine F.

“…Regardless of fat content in the diet, the doses of hydroxycut used significantly decreased fasting serum concentrations of cholesterol, triacylglycerol (TAG), low-density lipoprotein (LDL) cholesterol, total apolipoprotein B (apo B), and LDL/high-density lipoprotein (HDL) cholesterol ratio. …”
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Hemodynamics of small aneurysm pairs at the internal carotid artery by Jou, Liang-Der

“…The rupture risk increases considerably for multiple aneurysms. …”
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Pravastatin plus L-arginine prevents adverse pregnancy outcomes in women with uteroplacental vascular dysfunction by Aleksandar Jurisic (17052408)

“…Efforts to develop effective treatments to protect pregnancies with abnormal UtA Dopplers would be of significant clinical benefit for mothers and their fetuses.…”

Post‐Operative Analgesics Score, Another Tool in the Quest for a Better Pain Management by Ruben Peralta (768896)

“…Understanding that a hot, dry summer increases the risk of forest fires contributes to enhanced vigilance.…”

Association of genetic polymorphisms in FTO with Overweight/Obesity and Type 2 Diabetes in the Lebanese Population by Maroun, Veronica

“…Background and aims: Overweight and obesity are a worldwide threat to health and quality of life as they increase the risk of many chronic diseases including type 2 diabetes mellitus (T2DM). …”
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The effect of GLP-1R agonists on the medical triad of obesity, diabetes, and cancer by Shahad Sabaawi Ibrahim (21842273)

“…While other GLP-1R agonists have shown promising outcomes in mitigating cancer progression, the association between some GLP-1R agonists and an increased risk of cancer remains a topic requiring more profound investigation. …”

The use of multi-task learning in cybersecurity applications: a systematic literature review by Shimaa Ibrahim (22155739)

“…<p dir="ltr">Cybersecurity is crucial in today’s interconnected world, as digital technologies are increasingly used in various sectors. The risk of cyberattacks targeting financial, military, and political systems has increased due to the wide use of technology. …”

Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study by M. S Ajimsha (21250760)

“…The NRS reading also revealed significant improvement in pain (P < 0.001). </p><h3>Conclusions</h3><p dir="ltr">An EMM approach based on fascial connectivity led to significant symptom improvement in all the studied patients. …”

5G Networks Security Mitigation Model: An ANN-ISM Hybrid Approach by Rafiq Ahmad Khan (5066180)

“…<p dir="ltr">The advent of Fifth-Generation (5G) networks has introduced significant security challenges due to increased complexity and diverse use cases. …”

Pharmacist-led educational interventions provided to healthcare providers to reduce medication errors: A systematic review and meta-analysis by Myriam Jaam (11014409)

“…They are widespread in healthcare systems and are linked to an increased risk of morbidity and mortality. Several strategies have been studied to reduce their occurrence including different types of pharmacy-based interventions. …”

Phosphorus supplement alters postprandial lipemia of healthy male subjects by Bassil, Maya

“…Phosphorus (P) is reported to improve insulin sensitivity, which is involved in lipid metabolism, and thus we were interested in determining the impact of phosphorus ingestion on postprandial lipemia, a recognized CVD risk factor. …”
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