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181
PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development
منشور في 2020"…<p dir="ltr">Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with mental retardation syndrome 4 type (HPMRS4). Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*), in a 3-year-old boy with unique novel clinical features. …"
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182
Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis
منشور في 2025"…Direct oral anticoagulants were associated with comparable recurrence and mortality rates versus warfarin (odds ratio [OR] 0.72, 95% confidence interval [CI] 0.15–3.43) and (OR 0.57, 95% CI 0.16–2.01), respectively. There was no significant difference in the safety outcomes (major and minor bleeding events), with a trend towards a decreased risk among direct oral anticoagulant treated cohorts (OR 0.3, 95% CI 0.08–1.1) and (OR 0.64, 95% CI 0.24–1.7), respectively.…"
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183
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
منشور في 2019"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"
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184
Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties
منشور في 2022"…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …"
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185
Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar
منشور في 2023"…The proportion of patients spending less than 8 hours in the OB ED observation beds rose from 74% in January 2022 to over 98% in 2023. Notably, there was a remarkable decrease in patients who Left Without Being Seen (LWBS) and in absconded patient rates from 2020 to 2023 (Figure 2).…"
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186
Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
منشور في 2019"…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …"
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187
Advanced direct air capture of CO<sub>2</sub> using air conditioning systems: a life cycle assessment
منشور في 2025"…The integrated system exhibits significantly reduced environmental impacts compared to a standalone DAC unit. …"
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188
The effect of the local inertial term on the fluid flow in channels partially filled with porous material
منشور في 2001"…Also, it is found that the deviation between the predictions of the transient and the quasi-steady models is more significant in the porous domain and the deviation decreases as the time proceeds.…"
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189
A Comparative study of Technical Efficiency in GCC Islamic Financial Institutions during the Global financial Crisis using Malmquist-Type Data Envelopment analysis
منشور في 2013"…The results suggest that generally GCC and non-GCC IFIs efficiency was not significantly affected by the financial crisis. However, Individual IFIs result showed that some bank has experienced increase or decrease of efficiency after the crisis. …"
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190
Swimming exercise improves short‐ and long‐term memories: Time‐course changes
منشور في 2021"…In this investigation, changes in the spatial hippocampal memory following a time-course of swimming exercise training were examined. …"
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191
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
منشور في 2021"…The tumor microenvironment (TME) contains several cell types, including fibroblasts, immune cells, adipocytes, stromal proteins, and growth factors, which play a significant role in supporting the growth and aggressive behavior of cancer cells. …"
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192
Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…<h3>Background </h3><p dir="ltr">Polypharmacy has become a global public health concern particularly in the elderly population. …"
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193
Nicotine induces resilience to chronic social defeat stress in a mouse model of water pipe tobacco exposure by activating BDNF signaling
منشور في 2020"…Even though WTS initially decreased anxiety-like behaviors, prolonged exposure after the completion of CSDS significantly induced anxiety-like behaviors. …"
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194
High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
منشور في 2023"…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …"
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195
Thermo-economic analysis of a novel P2X polygeneration system for hydrogen, ammonia, and methanol production with near-zero emissions
منشور في 2025"…The system's levelized cost of hydrogen (LCOH) decreases significantly from $1.70/kg to $0.80/kg, and the levelized cost of electricity (LCOE) decreases from 4.30 ¢/kWh to 3.30 ¢/kWh. …"
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196
High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
منشور في 2023"…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …"
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197
Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
منشور في 2018"…This paper illustrates the many strategies to bridge the deficiency energy gap in three categories; 1) increase PV panel energy production by optimizing the orientation, inclination angle, manual tracking, enhanced microcontrollers and inverters, 2) increase PV panel efficiency from better manufacturers, 3) increase the area of PV panel installation on the building fabric and exploring options beyond the building footprint at the community level. …"
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198
Hypoglossal nerve stimulation for obstructive sleep apnea in adults: An updated systematic review and meta-analysis
منشور في 2024"…</p><h3>Methodology</h3><p dir="ltr">A systematic search was conducted across the databases to collect baseline and postoperative outcome measures. …"
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199
COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health
منشور في 2018"…Feasibility and acceptability findings indicated that the COPE program was a positive experience for teens. Significant decreases in depression and anxiety, and increases in QOL were also reported. …"
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200
Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…<p dir="ltr">Correction to: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study. <a href="https://doi.org/10.1371/journal.pone.0234386" target="_blank">https://doi.org/10.1371/journal.pone.0234386</a>, published online 11 June 2020.…"