Table 5_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx حسب Zhijian Zha (19451405)

"…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"

Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx حسب Jingjing Chen (293564)

"…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…"

Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif حسب Meirong Feng (22089665)

"…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …"

Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

"…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …"

Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

"…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …"

Table 5_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

"…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …"

Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

"…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …"

Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

"…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …"

Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx حسب Leyi Wang (408009)

"…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …"

Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden... حسب Matej Stuhec (5643284)

"…The number of PIMs also significantly decreased (p < 0.001), with reductions of 29.5% (from 308 to 217) based on the Priscus List and 17.5% (from 343 to 283) according to the Beers Criteria. …"

H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin. حسب Aditya Parmar (22331873)

"…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. …"

Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

"…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"

Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

"…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"

Table 1_Assessment of various salt water stresses with mineralization on plant growth and antioxidants activity to regulate oxidative stress and ROS scavenging of halophyte ice pla... حسب Xinchao Ma (22249096)

"…The results indicated that the T6 treatment (saline-alkali solution of 30 g/L) strongly decreased the plant height, stem thickness, leaf area and SPAD value of ice plants, and obviously suppressed the shoot and root biomass with the increase in salinity. …"

Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip حسب Alessia Cavallo (13036581)

"…Th1/Th17 cytokines significantly inhibited the high calcium-induced synthesis of phospholipids (PCs, PEs, SMs), and short-chain ceramides, while the synthesis of ceramides with medium to long carbon chains was upregulated. …"

Supplementary Material for: Words versus strands: Reliability and stability of concordance rates of self-reported and hair-analyzed substance use of young adults over time حسب Janousch C. (19792158)

"…Hair analysis-derived 3-month prevalence rates of cocaine (9%/23%) and ketamine (2%/6%) strongly increased over time, while decreasing for codeine (11%/8%). …"

Optimisation of read depth, DNA quantity, and unique alternate observation threshold. حسب Melinda L. Tursky (20790436)

"…I: The CV of variant size quantitation across independent replicates, which displayed a strong negative correlation to variant size (dotted lines indicate 95% confidence interval). J-L: Increasing unique alternative observation (UAO) thresholds for variant calls increased detection rate of rare variants (J), but markedly decreased the number of variants passing the threshold (K) and therefore reduced detection of true positive variants in reference standards (L). …"

Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis حسب Shivam Kumar Pandey (22295532)

"…Furthermore, LPS and FeSO₄ significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …"

Data Sheet 1_Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma.docx حسب Ângela Marques-Magalhães (20924831)

"…We found that MLo-1508 significantly decreased RCC cell viability while inducing apoptosis in a dose-dependent manner without cytotoxicity for non-malignant cells. …"

Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets حسب Karl Knipper (15016346)

"…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"