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significant increases » significant increase (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
increases decrease » increased release (Expand Search)
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19561
Data Sheet 1_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx
Published 2025“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. Regarding app usage, data entries decreased significantly from the first quarter to the second quarter but subsequently stabilised (p = 0.001). …”
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19562
Table 2_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”
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19563
Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX
Published 2024“…Additionally, baicalin at an appropriate dosage was found to increase levels of SOD, GSH, CAT, ACP, and AKP in yellow catfish (P < 0.05), while simultaneously decreasing MDA accumulation and the mRNA expression of inflammatory markers such as Keap1, IL1, IFN-γ, and TNF-α, (P < 0.05). …”
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19564
Supplementary file 1_Assessing pteropod shell dissolution to advance ocean monitoring techniques: a methods comparison of SEM, CT, and light microscopy.zip
Published 2025“…<p>Pteropods are marine planktonic snails that are used as bioindicators of ocean acidification due to their thin, aragonitic shells, and ubiquity throughout the world’s oceans; their responses include decreased size, reduced shell thickness, and increased shell dissolution. …”
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19565
Image 3_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg
Published 2025“…Nevertheless, due to the aging population, the absolute number of patients is expected to increase.</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”
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19566
Data Sheet 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx
Published 2025“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”
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19567
Image 4_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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19568
Table 5_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”
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19569
Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx
Published 2025“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”
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19570
Table 1_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.docx
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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19571
Data Sheet 2_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx
Published 2025“…At 12 months, the median change in HbA1c levels did not differ significantly between groups. Regarding app usage, data entries decreased significantly from the first quarter to the second quarter but subsequently stabilised (p = 0.001). …”
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19572
Table 12_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”
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19573
Image 2_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg
Published 2025“…Nevertheless, due to the aging population, the absolute number of patients is expected to increase.</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”
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19574
Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx
Published 2025“…Additionally, it impacted the dysregulation of lipid metabolism and inflammatory response pathways, significantly inhibited hepatic stellate cell (HSC) activation, and reduced ECM accumulation.…”
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19575
Table 6_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”
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19576
Table 3_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”
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19577
Image 1_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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19578
Image 3_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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19579
Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX
Published 2024“…Additionally, baicalin at an appropriate dosage was found to increase levels of SOD, GSH, CAT, ACP, and AKP in yellow catfish (P < 0.05), while simultaneously decreasing MDA accumulation and the mRNA expression of inflammatory markers such as Keap1, IL1, IFN-γ, and TNF-α, (P < 0.05). …”
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19580
Image 2_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”