Table 1_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.docx by Sielke Caestecker (20749481)

“…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…”

Data Sheet 1_The association between the gut microbiome and antituberculosis drug-induced liver injury.docx by Shengfei Pei (20852069)

“…</p>Results<p>Following anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P < 0.05). …”

Supplementary file 1_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…In vivo experiments showed that AM-CO could induce autophagy, an increase in LC3II expression and a decrease in P62 expression. …”

Supplementary file 2_Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy.pdf by Rui Zhang (13940)

“…In vivo experiments showed that AM-CO could induce autophagy, an increase in LC3II expression and a decrease in P62 expression. …”

Data Sheet 1_Antarctic krill habitat suitability variation in the Southern Ocean over 20 years.pdf by Yiyang Tan (18227048)

“…However, habitat suitability in the Weddell Sea has shown a marked decrease. Although climate change has produced mixed effects on krill habitats due to the varying responses of krill different life stages to environmental parameters, this study overall highlights a degradation of krill habitat in the Southern Ocean over the past two decades. …”

Data Sheet 1_Enhancing AAV-microdystrophin gene therapy after repeat dosing by blocking phagocytosis.docx by Rita Spathis (187690)

“…</p>Results<p>Viral load was significantly increased by 77-fold in white blood cells after two rAAV9-microdystrophin doses compared to mice receiving a single dose. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”

Management of asthma exacerbations in pediatric emergency departments across the United States by Melisa S. Tanverdi (17948353)

“…Most (74.9%) encounters resulted in ED discharge with a downward trend of visits for exacerbations per 1,000 ED visits of −9.77, 95% CI [–9.99,-9.54], increase in disposition to intensive care unit of 2.01 [1.87,2.41] and decrease in home/other of −3.77 [–4.34,–3.20]. …”

Data Sheet 1_Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function.docx by Amy K. Stark (20470996)

“…</p>Results<p>Prostaglandin E2 (PGE2) stimulation of retinal endothelial monolayers caused a decrease in barrier permeability in electric cell-substrate impedance sensing (ECIS) assays and dextran flux assays. …”

Table 1_Epidemiological study of thyroid cancer at global, regional, and national levels from 1990 to 2021: an analysis derived from the Global Burden of Disease Study 2021.docx by Lu Zhang (50563)

“…</p>Results<p>In 2021, there were an estimated 2 million (95% UI: 1.8, 2.2) cases of thyroid cancer worldwide, with an age-standardized prevalence rate of 23.1 (95% UI: 20.7, 25.6) per 100,000 individuals, reflecting a 55% increase since 1990. The global mortality from thyroid cancer in 2021 was 44,800 (95% UI: 39,900, 48,500), with an age-standardized rate of 0.5 per 100,000 people (95% UI: 0.5, 0.6), marking a 7% decrease since 1990. …”

Clinical and Imaging Characteristics of Posterior Scleritis in Children by Ayala Katzir (20605679)

“…Initial echography showed increased posterior scleral thickness (mean±SD 2.9 ± 0.68 mm) with a significant reduction four ± 2 months later (mean±SD 1.85 ± 0.62 mm). …”

Table 1_Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives... by Haixiao Jiang (12013904)

“…</p>Results<p>Our findings showed a significant decrease in the diversity and even distribution of microorganisms in the HE group when compared to the HC and NE groups. …”

Image 2_Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives... by Haixiao Jiang (12013904)

“…</p>Results<p>Our findings showed a significant decrease in the diversity and even distribution of microorganisms in the HE group when compared to the HC and NE groups. …”

Image 1_Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives... by Haixiao Jiang (12013904)

“…</p>Results<p>Our findings showed a significant decrease in the diversity and even distribution of microorganisms in the HE group when compared to the HC and NE groups. …”

Table_2_Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies–Solanum tuberosum interactions.docx by Lauriane Giroux (19779051)

“…Co-cultivation with potato microtubers induced the accumulation of S. scabies proteins implicated in siderophore pyochelin biosynthesis, nitrite production and oxidative stress perception and response. The increase in the abundance of proteins related to pyochelin biosynthesis was consistent with a significant decrease in the iron content in the culture medium, as well as with induction of expression of pyochelin biosynthesis genes. …”

Table_1_Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies–Solanum tuberosum interactions.docx by Lauriane Giroux (19779051)

“…Co-cultivation with potato microtubers induced the accumulation of S. scabies proteins implicated in siderophore pyochelin biosynthesis, nitrite production and oxidative stress perception and response. The increase in the abundance of proteins related to pyochelin biosynthesis was consistent with a significant decrease in the iron content in the culture medium, as well as with induction of expression of pyochelin biosynthesis genes. …”

Table_3_Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies–Solanum tuberosum interactions.docx by Lauriane Giroux (19779051)

“…Co-cultivation with potato microtubers induced the accumulation of S. scabies proteins implicated in siderophore pyochelin biosynthesis, nitrite production and oxidative stress perception and response. The increase in the abundance of proteins related to pyochelin biosynthesis was consistent with a significant decrease in the iron content in the culture medium, as well as with induction of expression of pyochelin biosynthesis genes. …”

Pond consolidation in the northwest Prairie Pothole Region changes water boatman (Hemiptera: Corixidae) species composition and reduces potential contribution to seasonal mass-migr... by Alexander Lapierre (22478656)

“…We found a non-significant decrease in species richness due to pond consolidation. …”

DataSheet1_OsPDIL1-5: dual role in promoting growth and development while modulating drought stress tolerance in rice (Oryza sativa L.).docx by Jilin Chen (19847928)

“…This discovery highlights the importance of GDDT as a pleiotropic gene with significant implications for both plant growth and drought resistance. …”

Table1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pat... by Boris Jakopovic (9265517)

“…The analysis of differentially expressed proteins in treated groups was done by use of bioinformatics tools and a decrease in ribosomal biogenesis (e.g., RPS3) and translation processes (e.g., RPL14) as well as an increase in unfolded protein response (e.g., DNAJC3), lipid metabolism (e.g., ACOT7), and the tricarboxylic acid cycle (e.g., FH) were observed.…”