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Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
Published 2016“…Cell cycle arrest in the S phase was detected with each compound separately, while combined treatment only increased the production of fragmented DNA. Both compounds induced apoptosis through the extrinsic pathway after 24 hours; however, after 48 hours, the intrinsic pathway was activated by topotecan treatment only. …”
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Effects of organic enrichment on macrofauna community structure: an experimental approach
Published 2013“…A reduction in abundance of individuals and species richness was found as between the control and organic-enriched treatments. Significant changes in assemblage structure were also found, mainly due to the decrease of the sensitive tanaid Apseudes talpa in organically-enriched treatments. …”
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Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma
Published 2023“…Intraperitoneal treatment of mice with COE (10, 25 or 50 mg/kg; 9 weeks) showed a non-significant decrease in tumor volume with respect to control, without adverse effects on liver and kidney function. …”
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Modulation of gut microbiota: The effects of a fruits and vegetables supplement
Published 2022“…The gut microbiome composition, measured by 16S rDNA sequencing, showed no difference in both alpha and beta diversities, whereas the LEfse analysis revealed a microbial shift after the treatment, with a decreased abundance of the genus <i>Ruminococcus</i> from the Lachnospiraceae family (<i>p</i> = 0.009), and the unclassified genus from the family Erysipelotrichaceae (UC36, <i>p</i> = 0.003) in the FVS group compared with the PLA group (confirmed by SIAMCAT analysis, AUC = 74.1%). …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome
Published 2011“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Application of Zn-ferrite towards thermochemical utilization of carbon dioxide: A thermodynamic investigation
Published 2021“…Effects of the influence of the ratio of the molar flow rate of inert sweep gas to the molar flow rate of ZnFe<sub>2</sub>O<sub>4</sub>, thermal reduction temperature, and gas-to-gas heat recovery effectiveness on thermal energy required to drive the cycle and the solar-to-fuel energy conversion efficiency are investigated at reduction nonstoichiometry of 0.1. The decrease in the reduction temperature is significant when the ratio of the molar flow rate of inert sweep gas to the molar flow rate of ZnFe<sub>2</sub>O<sub>4</sub> increases from 10 to 30. …”
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Assessment of the use of dolomite for the recovery of ammonia from field landfill leachate. (c2019)
Published 2019“…However, using dolomite calcined at 950 °C with the same phosphate source showed a significant decrease in removal efficiency to 44%, while using dolomite calcined at 750 °C (under continuous CO2 injection) resulted in a removal efficiency of 37%. …”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…Mutational incorporation into a Bioluminescence Resonance Energy Transfer (BRET)-based biosensors, which detects ligand-induced conformational changes, showed altered GAF domain conformation and increased EC50 for cGMP-induced conformational changes. …”
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Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review
Published 2022“…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …”
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The downsides of information systems security policy compliance efforts
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Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN)
Published 2004“…After 7 days of infusion, apoptosis increased in the TPN+L at a significantly higher rate compared with control and TPN-L groups ( p <0.05). …”
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Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions
Published 2017“…Temperature affects significantly the rheological behavior of neat water Wyoming Na-bentonite dispersions. …”
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Hydrogen energy systems: Technologies, trends, and future prospects
Published 2024“…Adoption at scale could decrease global <i>CO</i><sub><em>2</em></sub><sub> </sub>emissions by up to 830 million tonnes annually. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…For extension (%) at peak load, a decreasing trend was found vs. stretch rate (R2 = 0.81; two-tailed p value = 0.037) where increasing the displacement rate from 1 mm/min to 500 mm/min corresponds to a 22% decrease in the relative elongation of the mesh. …”
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