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141
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”
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142
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…<p dir="ltr">Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. …”
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143
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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144
Phase-separated polyvinylidene fluoride/ZnO composite microspheres as sunlight-driven photocatalysts
Published 2024“…Significant implications are anticipated in pollution control and environmental remediation through the purification of industrial wastewater.…”
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145
The Impact of Nutritional Supplementation During Pregnancy on the Incidence of Gestational Diabetes and Glycaemia Control
Published 2022“…The release of placental hormones during pregnancy induces/ increases maternal insulin resistance and promotes nutrition utilization by the fetus. …”
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146
Symptoms of depression and anxiety in anorexia nervosa
Published 2014“…The relationship between these clinical manifestations and the biological changes caused by starvation is not well understood. …”
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147
Proteome analysis of Candida albicans cell wall mutants. (c2011)
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148
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”
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149
Risk Assessment of the Impact of Heavy Metals in Urban Traffic Dust on Human Health
Published 2023“…<p dir="ltr">Excessive exposure to heavy metals induces potential adverse health impacts in humans. …”
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150
Substituted 2-Aminobenzothiazoles Salicylidenes Synthesis and Characterization as Cyanide Sensors in Aqueous Medium
Published 2018“…Acidic anions H2PO4<sup>−</sup> and H2AsO4<sup>−</sup> displayed significant interference with the interaction of cyanide and sensors 1 and 2. …”
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151
Photobiomodulation: A Systematic Review of the Oncologic Safety of Low-Level Light Therapy for Aesthetic Skin Rejuvenation
Published 2023“…There are no relevant clinical trial data linking PBM with any significant adverse events, including the finding of a new or recurrent malignancy.…”
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152
Highly selective adsorption of gases on functionalized spin-polarized dichalcogenide alloy
Published 2025“…Doping of MoSeS with Co induces its selective gas adsorption as a result of variation in adsorption energies which can be utilized to fabricate selective gas detectors. …”
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153
Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
Published 2017“…These findings have significant policy implications for the provision of guidance to policymakers in identifying optimal energy mixes and in pursuing realistic goals to enhance renewable energy penetration and to contribute to the current efforts of tackling climate change.…”
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154
Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
Published 2021“…However, for hydrophobic colloids, changes in solution chemistry significantly increase colloid retention where the colloid interaction become attractive with the increase in ionic strength and decrease in pH values. …”
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155
Competition vs cooperation: An agent based model for sustainable tomatoes’ import system
Published 2024“…Based on the research findings, a competitive global market can bring economic benefits to Qatar as an importing nation, but this approach also entails substantial <u>water consumption</u> and results in significant environmental emissions. Conversely, collaboration among exporting countries demonstrates a potential 20% reduction in water usage and a 15% decrease in environmental emissions compared to the competitive scenario, offering enhanced environmental performance albeit at<u> higher economic costs</u>. …”
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156
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
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157
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…It may assist policymakers of the Dubai government to develop and implement systematic changes into the current risk management processes. …”
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158
Causes of Delay in Construction Projects in Oil and Gas Construction Industry
Published 2017“…With regard to design, the contractor’s need to decrease construction costs through a cheaper design was found to be a factor in design changes. …”
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159
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published 2021“…<p dir="ltr">Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. …”
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160
Early degradation of silicon heterojunction PV modules installed on horizontal single-axis trackers in desert climate
Published 2025“…These findings showed an early degradation of 62 % of the inspected PV modules induced by their field exposure to a desert climate. …”