Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"
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A novel virtual patient approach for cross-patient multimodal fusion in enhanced breast cancer detection حسب Younes Akbari (16303286)

"…<p>Multimodal medical imaging combining conventional imaging modalities such as mammography, ultrasound, and histopathology has shown significant promise for improving breast cancer detection accuracy. …"

An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity حسب Wang, Wei

"…Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for treatment. Retinoids regulate a multitude of biological processes. In addition, retinoic acid can reverse premalignancy, significantly decrease second primary tumors and provide a treatment benefit in head and neck, lung, esophagus, colon and bladder cancer. …"
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The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis حسب Hoda Gad (6470522)

"…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …"

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma Younes (6424865)

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"

Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens حسب Sheraz Ahmed Bhatti (9759633)

"…Dietary OTA at all the tested levels induced the hepatic and renal tissue injury as indicated by significant decreased total antioxidant capacity in these organs along with significant decreased (p ≤ 0.05) serum concentrations of total proteins and albumin. …"

Comparative effects of CO₂ exposure on limestone and sandstone relevant to carbon sequestration in subsurface reservoirs حسب Osama Massarweh (17012217)

"…While XRD analysis detected mild mineralogical changes, SEM analysis (at magnifications reaching up to 50,000×) revealed significant microstructural degradation, particularly pronounced in sandstone. …"

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

"…Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …"

A Neighborhood Framework for Resource-Lean Content Flagging حسب Sheikh Muhammad Sarwar (19517701)

"…<p dir="ltr">We propose a novel framework for cross- lingual content flagging with limited target- language data, which significantly outperforms prior work in terms of predictive performance. …"

A customised fetal growth and birthweight standard for Qatar: a population-based cohort study حسب Thomas Farrell (3933833)

"…The main pathological factors were preexisting diabetes (increase by +175.7 g) and smoking (decrease by −190.9 g). …"

Fixing a heart valve حسب Nature Research (16552612)

"…All of these factors significantly increase the rate of complications following valve replacement, so valve repair is a more viable option in these parts of the world. …"

Improving the performance of a commercial absorption cooling system by using ejector: A theoretical study حسب Hamza K. Mukhtar (17821004)

"…An improvement of 70.6% in the COP was obtained at the design condition. A parametric analysis was implemented to study the significance of the key parameters in the RACS performance. …"

A clustering metaheuristic for large orienteering problems حسب Almiqdad Elzein (13141038)

"…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Shuja Mohd Reagu (12051406)

"…</p><h3>Results</h3><p dir="ltr">15.7% respondents report intent to not breastfeed. 21.4% respondents reported obsessive–compulsive symptoms. 77.3% respondents believed the biggest source of infection was from others while as only 12% of the respondents believed that the source of infection was through breastfeeding and 15.7% believed the vertical transmission as the main source of risk of transmission.</p><h3>Conclusions</h3><p dir="ltr">The rates of Obsessive–compulsive symptoms were increased and the rates of intent to breastfeed were decreased when compared with pre pandemic rates. …"

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial حسب Hourani, R.

"…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …"
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Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis حسب Ayman El-Menyar (440103)

"…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …"

Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion حسب Al-Dimassi, Saleh

"…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …"
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Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study حسب Mona Metwally El-Sayed (17725127)

"…</p><p><br></p><h3>Results</h3><p dir="ltr">A statistically significant decrease in anxiety level among the study group compared to the control group (Pre = 16.68 (7.35), immediate = 6.65 (2.89), post three-month = 7.68 (2.75), p=<0.001 and effect size = 0.715). …"

The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …"