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يعرض 1 - 20 نتائج من 289 نتيجة بحث عن '(( significant interaction profile ) OR ( significant ((we decrease) OR (linear decrease)) ))', وقت الاستعلام: 0.13s تنقيح النتائج
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

    منشور في 2025
    "…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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    Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning حسب Noaman Khan (19810050)

    منشور في 2025
    "…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …"
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    Analysis of the Capacitor-Less D-STATCOM for Voltage Profile Improvement in Distribution Network With High PV Penetration حسب Wesam Rohouma (16904871)

    منشور في 2022
    "…The contribution of this paper is a detailed analysis and impact study of the capacitor-less D-STATCOM in high PV penetration distribution networks. The significance of this paper is that it studies the behavior of the power electronics converter and its interaction with the power systems without assuming or neglecting details of either. …"
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    Interactions of black carrot concentrate powder as a natural coloring agent with gelatine and sucrose in model gummy samples حسب Ilyas, Atalar

    منشور في 2025
    "…BCCP x gelatin and BCCP × sucrose interactions were determined to be significant for texture parameters such as hardness, gumminess, chewiness, and L∗, a∗, b∗, and chroma values (P < 0.05). …"
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    Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

    منشور في 2023
    "…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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    Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women حسب Vijay, Ganji

    منشور في 2021
    "…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…"
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    Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women حسب Vijay Ganji (8710491)

    منشور في 2021
    "…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"