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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Special Issue: Empowering eHealth with Smart Internet of Things (IoT) Medical Devices
Published 2019“…IoT helps to store data for millions of patients and perform analysis in real-time, promoting an evidence-based medicine system. …”
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Hybrid deep learning based threat intelligence framework for Industrial IoT systems
Published 2025“…A significant challenge currently confronting the Industrial Internet of Things (IIoT) is the increasing prevalence of sophisticated IoT malware threats and attacks. …”
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UAV-based relay system for IoT networks with strict reliability and latency requirements
Published 2021“…This letter optimizes the number of UAVs and their positions and decides on the IoT-to-UAV associations and radio resource allocation while allowing IoT association with multiple UAVs using orthogonal frequency division multiple access. …”
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Prioritizing the multi-criterial features based on comparative approaches for enhancing security of IoT devices
Published 2023“…This research highlights the authentication feature of IoT devices from literature studies and evaluates the significant feature using COPRAS approach to assist organization in enhancing security of IoT devices.…”
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Prioritizing the multi-criterial features based on comparative approaches for enhancing security of IoT devices
Published 2023“…This research highlights the authentication feature of IoT devices from literature studies and evaluates the significant feature using COPRAS approach to assist organization in enhancing security of IoT devices.…”
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Prioritizing factors for the adoption of IoT-based smart irrigation in Saudi Arabia: a GRA/AHP approach
Published 2024“…However, the widespread implementation of an IoT-based Smart Irrigation System (I-SIMS) poses a multifaceted and intricate challenge in KSA. …”
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Security Assessment of Low-Resource Edge Devices for IoT Systems
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IoT empowered smart cybersecurity framework for intrusion detection in internet of drones
Published 2023“…In recent years, there has been a significant increase in the utilization of IoT-enabled drone data management technology. …”
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Protecting Smart Homes: A study on AI approaches to Detect Malwares and Developing a Two Factor Authentication System Based on SRAM PUF For Smart Home Users in UAE
Published 2025“…Due to the rapid adoption of smart technologies in smart homes, the Open Web Application Security Project has identified weak or easily guessable passwords as a significant vulnerability in IoT devices, based on real-world incidents. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”