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161
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
منشور في 2015"…In the presence of arachidonic acid, additional eicosanoids generated by 12/15-LOX, including 12- and 11-HETEs, were significantly increased. Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …"
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162
Student Wellbeing Conceptualisation and Practice: Policy Overview, Stakeholders’ Perceptions and a Proposed Evaluation Tool for UAE Private Schools
منشور في 2021"…Despite the resulting academic and policy interest that revolves around wellbeing, it is still a narrowly defined concept that lacks definition and practice guidance. This study investigates conceptualisation of student wellbeing and related practices in the UAE private school sector through (1) identifying and analysing the relevant policy frame that guides student wellbeing promotion, (2) exploring the perceptions of parents, teachers, school leaders and students regarding their understanding of student wellbeing and the practices followed by schools to enhance it, (3) determining significant factors that underline student wellbeing conceptualisation and practices, and (4) proposing a tool to facilitate schools’ self-evaluation and enhancement of student wellbeing. …"
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163
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164
Total and segmental liver volume variations
منشور في 2015"…Discussion There is clinically significant interpatient variation in hepatic volumes. …"
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article -
165
PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
منشور في 2019"…<div><p>Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. …"
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166
Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers
منشور في 2023احصل على النص الكامل
doctoralThesis -
167
Assessment of sustainable construction in Lebanon
منشور في 2012"…However, these efforts were not enough to have a significant impact on these industries and resulted merely in voluntary guidelines rather than serious measures to reduce energy usage and pollution. …"
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article -
168
Attitudes, motivators, and barriers toward influenza vaccination for children: a study from a conflict-ridden country
منشور في 2024"…<h3>Background</h3><p dir="ltr">Despite the increased recommendations for influenza vaccination, particularly among high-risk groups such as young children, Yemen lacks an influenza vaccination program, and the influenza vaccine is not included in the national immunization regime. …"
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169
Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials
منشور في 2024"…However, its effectiveness in improving histologic fibrosis, while showing numerical trends, still lacks statistical significance. Larger and longer NASH trials are warranted to enhance the robustness of the evidence.…"
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170
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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171
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
منشور في 2017"…Over-expression of MMP-8 WT but not MMP-8 EA in β6-1089 cells increased adhesion to ECM proteins and reduced migration. …"
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172
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"
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173
Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd...
منشور في 2021"…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3–74·0) in 2000 to 37·1 (33·2–41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8–29·5) in 2000 to 17·9 (16·3–19·8) in 2019. …"
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174
Oman's Labour Force: An Analysis of Gender in Management.
منشور في 2014"…Hence, this is a descriptive study and lacked advanced statistical techniques for comparison and relationship analysis. …"
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article -
175
The current state of female leadership in the United Arab Emirates
منشور في 2013"…Research limitations: The database utilized did not contain completed company data; specifically, any response variable; hence, the study was descriptive in nature and lacked advanced statistical techniques for comparison and relationship analysis. …"
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article -
176
An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat...
منشور في 2022"…However, in clay loam soils, NT lacked all criteria for good physical quality indications in opposition to RT. …"
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masterThesis