Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx حسب Ping-Heng Zhang (21785162)

"…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …"

Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx حسب Na Zhu (331131)

"…After adjusting for all confounders, LC9 was significantly and negatively associated with both MASLD (OR = 0.59, 95% CI: 0.54–0.64) and hepatic fibrosis (OR = 0.66, 95% CI: 0.45–0.97), with each 10-point increase in the LC9 score decreasing the prevalence by 41% and 34%, respectively. …"

Data Sheet 1_Investigating the spatial limits of somatotopic and depth-dependent sensory discrimination stimuli in rats via intracortical microstimulation.docx حسب Thomas J. Smith (224833)

"…Results showed that when spatial distances between stimuli patterns were decreased, the rats had reduced discriminable accuracy, suggesting greater difficulty when differentiating closely positioned stimuli. …"

Image 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…Notably, its prognostic significance appears to be tumor-type specific, associating with either favorable or poor outcomes depending on the cancer context.…"

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx حسب Juanzhao Cao (22651742)

"…Population growth and epidemiological changes contributed significantly to the increase in the burden of OUD.</p>…"

Table 1_The health burden of disease attributable to low calcium intake: a comprehensive analysis of trends and socioeconomic impacts from 1990 to 2021.docx حسب Yanping Wang (275956)

"…</p>Conclusion<p>DLC significantly increases the incidence of CRC, while its impact on prostate cancer incidence is relatively minor and shows a negative correlation. …"

Table 1_Association of magnesium depletion score with serum anti-aging protein Klotho in the middle-aged and older populations.docx حسب Zhijie Zhuang (17669958)

"…</p>Results<p>The weighted average serum Klotho concentrations decreased significantly across MDS groups (low: 864.50, middle: 805.67, high: 755.02 pg.…"

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif حسب Marcela Rios-Carlos (22759823)

"…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …"

S1 Raw data - حسب Dao-Cheng Zhou (20314697)

"…All-cause and CVD mortality gradually decreased with increasing ideal LE8 metrics. LE8 was not significantly associated with cancer mortality. …"

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf حسب Mengyuan Dai (9747317)

"…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …"

Image 4_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…Notably, its prognostic significance appears to be tumor-type specific, associating with either favorable or poor outcomes depending on the cancer context.…"

Image 4_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg حسب Fushan Lu (20413670)

"…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …"

Image 3_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg حسب Fushan Lu (20413670)

"…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …"

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv حسب Jie Zheng (31208)

"…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …"

Data Sheet 2_The effect of training intervention based on health belief model on self-care behaviors of women with gestational diabetes mellitus.pdf حسب Fatemeh Mohammadkhah (14157844)

"…Also, the comparison of averages of blood sugar levels after the intervention in the two groups indicated that fasting blood sugar level, A1C hemoglobin, and blood sugar levels measured 2 h after the meal significantly decreased in the intervention group (p < 0.001). …"

DataSheet1_Reduce the application of phosphorus fertilizer in peanut fields and improve its efficiency by using iron modified biochar to adsorb phosphorus recovery products.docx حسب Junxiao Zhang (421908)

"…While the phosphorus recovery efficiency (REP) does not significantly differ between FeBP-P2 and B1P1 treatments, both are superior to B0P1. …"

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Table 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx حسب Paolo Romania (399007)

"…Notably, its prognostic significance appears to be tumor-type specific, associating with either favorable or poor outcomes depending on the cancer context.…"

Image 5_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg حسب Fushan Lu (20413670)

"…However, pretreatment with SBP followed by H₂O₂ inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H₂O₂–induced cells. …"

Data Sheet 1_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20... حسب Xin Gong (592328)

"…Disease burden varies significantly across SDI regions, suggesting that preventive measures should be tailored to specific SDI levels.…"