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221
Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
منشور في 2025"…AB-FUBINACA treatment also causes a significant dose related decrease in sperm viability. …"
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222
In-situ grown ternary metal hydroxides@3D oriented crumpled V₂C MXene sheets for improved electrocatalytic oxygen evolution reaction
منشور في 2024"…Furthermore, we have utilized a more accurate value of half-cell standard reduction potential of the Hg/HgO electrode in the Nernst equation to represent all test voltages and to determine the overpotential values. …"
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223
Examining the Correlation Between Out-On-Pass Privileges and Post-Discharge Urine Drug Test Outcomes in an Addiction Rehabilitation Center in Qatar
منشور في 2025"…While relapse remains a significant challenge, OOP may contribute to extended abstinence periods and reduced relapse rates.…"
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224
Recovery of business intelligence systems
منشور في 2018"…In the best case, the proposed algorithm requires 0.43 ms, which is 86 times faster than the fastest recent work. This is a significant reduction of execution time compared with other available approaches. …"
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225
Functional Characterization of Novel <i>MC4R </i>Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar
منشور في 2023"…In vitro analysis of the functional impact of these variants showed a significant reduction in cell surface receptor expression and impaired extracellular ligand binding activity, leading to reduced cAMP production. …"
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226
Biochemical Characterization of Halotolerant Bacillus safensis PM22 and Its Potential to Enhance Growth of Maize under Salinity Stress
منشور في 2022"…Maize plants inoculated with PM22 also exhibited a significant reduction in electrolyte leakage, hydrogen peroxide, malondialdehyde, glycine betaine, and proline contents compared to non-inoculated control plants. …"
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227
Masked phenomenon: renal and cardiovascular complications; review and updates
منشور في 2024"…The potential extension of the observed benefits of MP therapy, including a reduction in end-organ damage, remains questionable.…"
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228
Tamsulosin plus Tadalafil compared with Tamsulosin alone for benign prostate hyperplasia in patients with or without erectile dysfunction: a meta-analysis and meta-regression of ra...
منشور في 2025"…Our analysis demonstrated that the combination therapy is associated with a greater reduction in overall IPSS (MD = − 2.78, 95% CI − 3.97 to − 1.59; P < 0.01), IIEF (MD = 2.98, 95% CI 1.64 to 4.33; P < 0.01), QoL score (MD = − 0.58, 95% CI − 0.86 to − 0.30; P < 0.01), PVR (MD = − 9.34, 95% CI = -15.52 to − 3.16; P < 0.01) and a significant improvement in Qmax (MD = 1.04, 95% CI 0.43 to 1.64; P < 0.01) as compared to tamsulosin alone. …"
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229
Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
منشور في 2025"…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …"
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230
The effect of colchicine on myocardial infarction: An updated systematic review and meta-analysis of randomized controlled trials
منشور في 2024"…Colchicine demonstrated statistically significant reduction in the composite of adverse cardiovascular events (RR = 0.75, 95 % CI: 0.60-0.94, P = 0.01, I2 = 47 %), and hospitalization urgency (RR = 0.46, 95 % CI: 0.31-0.68, P = 0.0001, I2 = 0 %) but statistically significant increment in adverse gastrointestinal events (RR = 1.86, 95 % CI: 1.14-3.02, P = 0.01, I2 = 79 %). …"
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231
Efficient self-attention with smart pruning for sustainable large language models
منشور في 2025"…However, their high computational demands result in significant environmental impacts, particularly in terms of energy and water consumption. …"
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232
Industrial Processes Performance Improvement using Six Sigma Principles and Tools
منشور في 2019"…Moreover, there has been a significant waste reduction and operational efficiency, which has greatly reduced the cost of operation and better customer retention. …"
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233
Exploring beyond numeric weight loss: The metabolic effects of semaglutide
منشور في 2025"…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. …"
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234
Macular Buckling for Myopic Traction Maculopathy: A Comprehensive Systematic Review and Meta-Analysis
منشور في 2025"…Axial length showed consistent reductions, with a mean long-term reduction of 2.88 mm (95% CI: 2.54-3.21). …"
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235
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi...
منشور في 2011"…Bone marrow (BM) transplantation experiments further revealed that LDLR⁻′⁻ mice reconstituted with AEBP₁⁻′⁻/LDLR⁻′⁻ BM cells (LDLR⁻′⁻/KO-BM chimera) display significant reduction of atherosclerosis lesions (en face: 2.0-fold, P = 0.0268; aortic roots: 1.7-fold, P = 0.05) compared with control mice reconstituted with AEBP₁⁺′⁺/LDLR⁻′⁻ BM cells (LDLR⁻′⁻/WT-BM chimera). …"
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236
The effect of colchicine on myocardial infarction: An updated systematic review and meta-analysis of randomized controlled trials
منشور في 2025"…Colchicine demonstrated statistically significant reduction in the composite of adverse cardiovascular events (RR = 0.75, 95 % CI: 0.60-0.94, P = 0.01, I<sup>2</sup> = 47 %), and hospitalization urgency (RR = 0.46, 95 % CI: 0.31-0.68, P = 0.0001, I<sup>2</sup> = 0 %) but statistically significant increment in adverse gastrointestinal events (RR = 1.86, 95 % CI: 1.14-3.02, P = 0.01, I<sup>2</sup> = 79 %). …"
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237
The role of tranexamic acid in orthognathic surgery: an umbrella review
منشور في 2025"…All reviews found that TXA significantly reduces intraoperative blood loss, with mean reductions ranging from approximately 94 mL to 265 mL, regardless of the administration route. …"
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238
RFX3 is essential for the generation of functional human pancreatic islets from stem cells
منشور في 2025"…Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …"
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239
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
منشور في 2021"…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …"
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240
Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd...
منشور في 2021"…<h3>Background</h3><p dir="ltr">Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. …"