The lung protein that tells all حسب Nature Research (16552612)

"…</p><p dir="ltr">Serum SP-D levels were significantly increased in all patients with COPD compared to the healthy cohort. …"

A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein حسب Natalie Landeck (414147)

"…Furthermore, using this assay we investigated h-asyn levels in brain tissue samples from patients with PD as well as PD dementia and found significant differences in pS129 h-asyn levels not only between disease tissue and healthy control samples but also between the two distinct disease states especially in hippocampal tissue samples.…"

Breast cancer cells and bone marrow mesenchymal stromal cells حسب Faour, Wissam H.

"…While co-culture assays with SaOS-2 increased the expression of osteoblastic markers in MCF-7 cells, SaOS-2 cell conditioned medium increased the expression of RANKL, PTHrP, VEGF and NOGGIN in MCF-7 cells. …"
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Tipping the Balance: Vitamin D Inadequacy in Children Impacts the Major Gut Bacterial Phyla حسب Parul Singh (191877)

"…<div><p>Vitamin D inadequacy appears to be on the rise globally, and it has been linked to an increased risk of osteoporosis, as well as metabolic, cardiovascular, and autoimmune diseases. …"

Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes حسب Faour, Wissam

"…Podocytes treated for 20 min with H2O2 (10−4 M), which mimics reactive oxygen species generation by cells challenged by hyperglycemic or enhanced Pgc conditions, significantly increased the levels of active p38 MAPK, AKT, JNK and ERK1/2. …"
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese حسب Abdelkrim Khadir (437074)

"…More interestingly, a 3-month physical exercise differentially affected HSP60 expression and the heat shock response but attenuated inflammation in both groups, as reflected by decreased endogenous levels of IL-6 and TNF-α. Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …"

5G Networks Security Mitigation Model: An ANN-ISM Hybrid Approach حسب Rafiq Ahmad Khan (5066180)

"…<p dir="ltr">The advent of Fifth-Generation (5G) networks has introduced significant security challenges due to increased complexity and diverse use cases. …"

Voluntary Adoption of Integrated Reporting in an Emerging Market: The Case of UAE حسب KURDY, DANIA MAHMOUD

"…Study Aim The increasing complexity and uncertainty in corporate environments necessitate enhanced transparency, particularly for investors seeking insights into value creation. …"
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Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials حسب Mohamed Mahmoud Marey (18560902)

"…No significant differences were detected in the aldafermin group regarding histologic endpoints, lipid profile, metabolic parameters, and overall adverse effects, except for the increased occurrence of diarrhea in the aldafermin 3 mg subgroup.…"

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats حسب Azar Hosseini (33501)

"…</p><h3>Results</h3><p dir="ltr">Our results show that isoprenaline increased the serum levels of cTnT, LDH, CK-MB, and CPK (p < 0.001) and elevated MDA levels (p < 0.001) in cardiac tissue. …"

Smart food supply chain management: A bibliometric and systematic review حسب Mona Jabor Al-Thani (22928782)

"…<p>The food supply chain (FSC) faces increasing pressure due to rising global demand, inefficiencies, food safety concerns, and sustainability challenges. …"

Experimental Verification of Low-Pressure Kinetics Model for Direct Synthesis of Dimethyl Carbonate Over CeO₂ Catalyst حسب G. Ibrahim (7601063)

"…The CO₂Fix analysis revealed that, at a conversion rate of 27%, the process can achieve a "net zero" state when operated at an approximate pressure of 30 bar, thereby supporting the viability of low-pressure synthesis. Increasing the conversion rate to levels exceeding 95% significantly enhances the CO₂Fix metric, potentially surpassing 3.5 or higher.…"

Intratumoral FoxP3⁺Helios⁺ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer حسب Azharuddin Sajid Syed Khaja (19720114)

"…In this preliminary study, we report that the majority of CD3⁺ T cells in the TME are CD4⁺ T cells with high co-expression of programmed death 1 (PD-1)/cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and PD-1/CD39 molecules. Levels of CD4⁺FoxP3⁺Helios⁺ Tregs were significantly increased in the TME. …"

A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats حسب Zeeni, Nadine

"…Furthermore, treatment with BDNF has been found to attenuate weight gain or even cause weight loss and appetite suppression in rats. The aim of this study was to look at the effect of nutrient intake on BDNF concentrations and cellular proliferation in the brain. …"
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase حسب Amira Othman (380131)

"…ROS generation and NOX2 expression were also measured in mice retinas. 12- and 15- HETE significantly increased permeability and reduced TER and ZO-1expression in REC. …"

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity حسب Mohammed R. Shaker (10316180)

"…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …"

Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress حسب Jing Ma (24574)

"…The concentration of malondialdehyde (MDA) and Cd accumulation (roots and shoots) increased significantly (P < 0.05) under the increasing levels of Cd in all genotypes of B. oleracea while antioxidant (enzymatic or non-enzymatic) capacity and nutritional status of the plants was decreased with varying levels of Cd in the sand. …"

Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample حسب Khazen, Georges

"…Results: Results showed that anxiety had the greatest effect on increasing the predisposition to ED, followed by stress level, BID, depression and restrained eating. …"
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The Interactions of Business Environment, Generic Strategy, Operations Strategy, and Business Performance in the Lebanese Industries حسب Ghazal, Ziad

"…The results confirmed the significance of the direct effects at the aggregate level. …"
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…The absence of dependence indicated that cytotoxicity levels seen may depend on the activity levels of these proteases, rather than on their expression levels. …"
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