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significant level » significance level (Expand Search), significance levels (Expand Search), significant gender (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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8861
Data Sheet 5_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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8862
Data Sheet 1_Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.pdf
Published 2024“…Investigation of the potential role of SDC4 in the pathogenesis of WB myopathy revealed a decreased tendency in SDC4 gene expression and increased shedding of its ectodomain. …”
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8863
Table 2_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx
Published 2025“…Subsequently, we discovered that DASH levels are significantly negatively correlated with waist circumference (WC), fasting plasma glucose (FPG), triglycerides (TG), and systolic blood pressure (SBP), while exhibiting a positive correlation with high-density lipoprotein cholesterol (HDL-C) through RCS curves and linear regression.…”
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8864
Table 2_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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8865
Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023)
Published 2025“…By 2023, younger children returned to pre-pandemic levels, while older children, particularly 8-16-year-old girls, remained at higher weights (OR23vs19: 1.2-1.5, p<0.001-0.002). …”
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8866
Table 7_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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8867
Image 2_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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8868
Data Sheet 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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8869
Data Sheet 4_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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8870
<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian...
Published 2025“…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca<sup>2+</sup> fluxes due to altered transcription of Ca<sup>2+</sup>-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …”
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8871
Table 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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8872
Table 5_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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8873
Image 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.jpeg
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”
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8874
Table 3_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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8875
Data Sheet 2_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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8876
DataSheet2_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.xlsx
Published 2024“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”
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8877
Table 13_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.docx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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8878
Data Sheet 1_Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression.pdf
Published 2025“…</p>Results<p>Immunofluorescence revealed significantly reduced ARL13B levels in α-SMA-positive cells as compared with Pan-CK-positive cells in an epiretinal membrane derived from retinal tears. …”
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8879
Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf
Published 2025“…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …”
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8880
Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx
Published 2024“…Moreover, our investigation demonstrated that increased expression of SMAD4 promoted the activating receptor NKG2D by elevating levels of YTHDF2. Ultimately, the SMAD4-YTHDF2 regulatory axis significantly enhanced the cytotoxicity of NK cells against human CRC cells.…”