Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx حسب Tianyao Li (7388201)

"…Furthermore, the phosphorylation levels of p38 and JNK in the MAPK pathway were significantly reduced, suggesting a key mechanism for its therapeutic effects.…"

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF حسب Huan Yu (140826)

"…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …"

Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx حسب Yonglei Liu (5485793)

"…</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …"

Image 2_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg حسب Wandi Ma (17295430)

"…H2 allele correlated with decreased levels of low-density lipoprotein cholesterol (LDL-C), apoB and lower atherogenic index (AI) in both groups, in addition to the GDM group also with lower total cholesterol (TC), whereas the G allele of rs4420638 correlated with increased triglyceride and decreased apoA1 levels.…"

Supplementary Material for: Camrelizumab combined with Lenvatinib and RALOX-HAIC for unresectable hepatocellular carcinoma (Cal Era): a prospective, single-arm, phase II trial حسب figshare admin karger (2628495)

"…Serum IL2, CXCL13, and CCL19 levels significantly differed between stable disease and partial response patients (P < 0.05 and |fold change| > 1.5). …"

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF حسب Huan Yu (140826)

"…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …"

Image 1_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg حسب Wandi Ma (17295430)

"…H2 allele correlated with decreased levels of low-density lipoprotein cholesterol (LDL-C), apoB and lower atherogenic index (AI) in both groups, in addition to the GDM group also with lower total cholesterol (TC), whereas the G allele of rs4420638 correlated with increased triglyceride and decreased apoA1 levels.…"

Data Sheet 1_Dietary supplementation with polypeptin and bioture improves growth, feed utilization, antioxidant capacity, and disease resistance in juvenile hybrid grouper (Epineph... حسب Futao Jing (22516817)

"…Serum biochemical parameters related to stress and hepatic function, including AST, ALT, LDH, TG, T-CHO, and cortisol, were significantly lower in supplemented groups. The levels of LZM, ACP, AKP, and IgM were significantly upregulated both at baseline and post-challenge, indicating enhanced humoral immunity. …"

Interaction of sex hormone receptors and calcium handling proteins in the left ventricle of patients with heart failure حسب Shuwei Ning (20484194)

"…Compared with the control group, the expression levels of sex hormone receptors and calcium handling proteins in HF patients were significantly decreased. …"

Table 1_Relationship between plasma atherogenic index and subclinical hypothyroidism: an analysis of NHANES data and animal experiment.docx حسب Qiwei Chen (1417807)

"…Animal experiments confirmed that compared with the CG, rats in the MG exhibited significantly higher levels of blood lipid, AIP and TSH, but lower levels of FT4 and FT3.…"

Table 2_Relationship between plasma atherogenic index and subclinical hypothyroidism: an analysis of NHANES data and animal experiment.docx حسب Qiwei Chen (1417807)

"…Animal experiments confirmed that compared with the CG, rats in the MG exhibited significantly higher levels of blood lipid, AIP and TSH, but lower levels of FT4 and FT3.…"

Data Sheet 1_Silicon (Si) foliar treatment modulates Capsicum annuum L. (green chilli) growth and stress responses under cadmium and lead stress.docx حسب Waquar Akhtar Ansari (7056191)

"…Interestingly, Si foliar application in Cd and Pb-treated chilli plants upregulates the transcript levels of POD, SOD, CAT, and GPX genes. Additionally, Si reduces the HM-induced phytotoxicity by decreasing Cd and Pb uptake in roots and shoots of chilli plants, as well as metal translocation (TF) and bioconcentration (BCF) factors. …"

Table 1_Biochar-based fertilizer increases soil nutrients and enhances tea quality: a metabolomics-based analysis.docx حسب Zhenyu Yang (427524)

"…Further metabolomics analysis revealed that BF2 treatment significantly elevated the levels of amino acids, including theanine, threonine, proline, valine, and glutamic acid, while decreasing catechins including C, EC, and EGCG, thus leading to reduced bitterness and astringency and enhanced freshness. …"

Image1_Efficacy and Safety of a Polysaccharide-Based Natural Substance Complex in the Treatment of Obesity and Other Metabolic Syndrome Components: A Systematic Review.TIF حسب Giuseppina Guarino (6795282)

"…Decreased lipid levels were observed in adults following a normocaloric diet who received PGR for 30 days. …"

Data Sheet 1_Impact of bacteroides uniformis on fatty liver hemorrhagic syndrome in dawu golden phoenix laying hens: modulation of gut microbiota and arachidonic acid metabolism.do... حسب Yu Zhang (12946)

"…Moreover, targeted metabolomic analysis showed that supplementation of B. uniformis significantly elevated 6-keto-PGF_1α and AA levels, along with significantly reduced levels of thromboxane B₂ (TXB₂), leukotriene D₄ (LTD₄), 8-isoprostaglandin F_2α (8-iso-PGF_2α), 12S-hydroxyeicosatetraenoic acid (12S-HETE), 15S-hydroxyeicosatetraenoic acid (15S-HETE), 9-S-hydroxy-octadecadienoic acid (9S-HODE), and 13-S-hydroxy-octadecadienoic acid (13S-HODE) (p < 0.05). …"

Data Sheet 1_Dihydroartemisinin-sodium taurocholate-PLGA nanoparticles: a novel therapeutic approach against cystic echinococcosis.docx حسب Aierpati Moheteer (21522284)

"…Furthermore, the DSP nanoparticles-H group significantly decreased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TBIL), direct bilirubin (DBIL), and alkaline phosphatase (ALP). …"

De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. حسب Sarfraz Shafiq (13259589)

"…<b>(C)</b> Volcano plot showing retroelement loci with increased (blue) and decreased (red) transcript levels in ATRX-null compared to control microglia. …"

Supplementary file 1_Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress.docx حسب Junhui Yu (8899847)

"…Biochemically, UGP significantly reduced the levels of liver collagen, triglycerides, and cholesterol (n = 6, p < 0.0001). …"

Supplementary information files for "Graphene oxide as an additive in aqueous lubricants for electric drive units: Synthesis, preparation, and tribological performance" حسب Reza Najjari Saadatabadi (16737153)

"…GO supernatant had a significantly lower particle size compared to GO redispersed at all pH levels. …"

Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg حسب Zhuwei Liang (8762337)

"…Interleukin-12 and interferon-gamma levels increased, whereas serum CAS-specific IgG1 and IgE levels decreased. …"