Image 2_Case Report: Is there an age cutoff beyond which PFO closure should not be offered?.jpeg by Eustaquio Maria Onorato (11277405)

“…Two-dimensional (2D) transthoracic/transesophageal echocardiography (TTE/TEE) color Doppler showed a significant right-to-left shunt (RLS) via a tunnel-type PFO associated with hypermobile floppy septum primum (HSP) and prominent Eustachian valve (EV). …”

Data Sheet 1_Global burden of disease for colorectal cancer due to diet low in whole grains from 1990 to 2021 and its projections to 2050: analysis of the global burden of disease... by Mei Yang (51996)

“…</p>Results<p>Between 1990 and 2021, the number of CRC deaths associated with a low proportion of whole grain diets worldwide increased by 82.94%, and disability adjusted life years increased by 70.3%. There is significant heterogeneity between regions: regions with high Social Population Index (SDI) have the highest decrease rate, while regions with low to medium SDI have the fastest increase rate. …”

Data Sheet 2_Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990–2021 analysis and future projections.docx by Ming Liu (105953)

“…</p>Results<p>From 1990 to 2021, the global burden of AGN among children and adolescents remained significantly high. In 2021, there were approximately 170,584 new cases, representing a decrease compared to earlier years, with an age-standardized incidence rate (ASIR) of 6.47 per 100,000 (95% UI: 4.79–8.45). …”

Data Sheet 1_Epidemiological trends and age-period-cohort effects on subarachnoid hemorrhage burden across the BRICS-plus from 1992 to 2021.docx by Liang Guo (95092)

“…Indonesia reported the highest age-standardized incidence rate (10.94 per 100,000 population) in 2021, while China displayed the most significant decrease, at 59.36%. The annual net drift in the SAH incidence rate ranged from −3.36%% for China to −0.50% for the Russian Federation among the eleven countries. …”

Data Sheet 3_Deep crustal composition and Late Paleozoic geotectonic evolution in West Junggar, China.pdf by Shenglin Xu (12076840)

“…During the Early Permian-Early Triassic period (272–250 Ma), magmatic activity decreased significantly, where the southwestern region experienced high-temperature, low-pressure, crustal thinning extension. …”

Data Sheet 4_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Image 5_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”

Image 1_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”

Figure S5 from Immunoproteasome Activation Expands the MHC Class I Immunopeptidome, Unmasks Neoantigens, and Enhances T-cell Anti-Myeloma Activity by Priyanka S. Rana (15136410)

“…Compound A induced a marked decrease in PD-1 surface expression, while no significant change was observed in TIM-3, CTLA-4, and LAG-3.…”

DataSheet1_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Table1_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table 1_The effectiveness of exercise interventions in the improvement of sleep in older adult people: a meta-analysis.docx by Di Geng (1681915)

“…Background<p>Sleep problems are prevalent among the older adult population, with a significant impact on their health and overall well-being. …”

Data Sheet 1_The impact of architectural modifications on relative resistance to fluid flow in ventricular catheters.pdf by Rajesh Kumar Madhavan (20634731)

“…</p>Results<p>With increasing hole and lumen diameter, we found a significant decrease in overall catheter relative resistance using DIH₂0 (P < 0.001 and P < 0.002 respectively, n = 5). …”

Table 1_Food waste management practices in hospital foodservices and their associated greenhouse gas emissions: potential for increased environmental sustainability.docx by Yee Man Janis Yip (21346568)

“…The median GHGs generated decreased after adopting the alternative strategy in all scenarios. …”

Data Sheet 2_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Table2_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Table2_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Image 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.pdf by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”

Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”

Supplementary file 1_Phase angle as a predictor of prolonged length of hospital stay and adverse outcomes in elderly medical inpatients: a retrospective cohort study.docx by Jia Liu (41593)

“…Adverse event rates across the PhA tertiles (T1–T3) were 32.9%, 18.6%, and 5.6%, respectively, indicating a significant decrease in event incidence as PhA values increased. …”