Showing 19,381 - 19,400 results of 21,342 for search '(( significant level decrease ) OR ( significant decrease decrease ))', query time: 0.52s Refine Results
  1. 19381

    Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx by Xinxin Li (281237)

    Published 2024
    “…Moreover, our investigation demonstrated that increased expression of SMAD4 promoted the activating receptor NKG2D by elevating levels of YTHDF2. Ultimately, the SMAD4-YTHDF2 regulatory axis significantly enhanced the cytotoxicity of NK cells against human CRC cells.…”
  2. 19382

    Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca... by Huihui Zhu (4483621)

    Published 2025
    “…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
  3. 19383

    Image 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.tiff by Sadia Hamera (22524803)

    Published 2025
    “…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
  4. 19384

    Data Sheet 1_An active ingredient from the combination of Corydalis Rhizoma and Paeoniae Radix Alba relieves chronic compression injury-induced pain in rats by ameliorating AR/Mboa... by Ze-Ming Wang (9572399)

    Published 2025
    “…</p>Results<p>The results demonstrated that YB60 significantly decreased inflammatory cytokine levels both in cellular models and rat serum, while concurrently elevating pain thresholds in CCI rats. …”
  5. 19385

    Table 11_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx by Linling Du (22827035)

    Published 2025
    “…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
  6. 19386

    Validation of FGF9 expression in external database and NRK-52E cells. by Donglin Yang (490406)

    Published 2025
    “…<p>(A) The expression of FGF9 in the GSE30122 database was significantly decreased. (B) The expression of FGF9 in the GSE96804 database was significantly decreased. …”
  7. 19387

    Knockdown of fatty acid binding protein 3 attenuates cerebral Ischemia-reperfusion injury <i>via</i> inhibiting neuronal apoptosis in mice by Jin-Jin Tian (22046330)

    Published 2025
    “…Moreover, FABP3 knockdown decreased the expression of pro-apoptotic proteins (Bax, cleaved-caspase-3) while increasing anti-apoptotic Bcl-2 levels. …”
  8. 19388

    Table 1_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.docx by Dongpo Li (3612152)

    Published 2025
    “…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
  9. 19389

    Image 3_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

    Published 2025
    “…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
  10. 19390

    Image 1_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

    Published 2025
    “…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
  11. 19391

    Image 2_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

    Published 2025
    “…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
  12. 19392

    Image 4_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg by Dongpo Li (3612152)

    Published 2025
    “…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
  13. 19393

    Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx by Qiqi Wu (4895728)

    Published 2025
    “…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
  14. 19394

    Image 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.tif by Fan Lin (625737)

    Published 2025
    “…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
  15. 19395

    Table 2_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx by Chao-Chao Chen (21090215)

    Published 2025
    “…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
  16. 19396

    Image 3_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff by Chao-Chao Chen (21090215)

    Published 2025
    “…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
  17. 19397

    Image 4_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

    Published 2025
    “…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”
  18. 19398

    Table 3_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx by Fan Lin (625737)

    Published 2025
    “…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
  19. 19399

    Table 1_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx by Chao-Chao Chen (21090215)

    Published 2025
    “…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
  20. 19400

    Data Sheet 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.... by Fan Lin (625737)

    Published 2025
    “…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”