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8941
Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip
Published 2025“…Reactive oxygen species (ROS) levels were measured using a ROS detection kit, while apoptosis was evaluated by flow cytometry and TUNEL assays. …”
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8942
Table 2_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx
Published 2025“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”
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8943
Table 2_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.xlsx
Published 2025“…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…”
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8944
Table 3_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.docx
Published 2025“…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…”
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8945
Table 1_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx
Published 2025“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”
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8946
Table 4_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xls
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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8947
Calibration curve.
Published 2025“…The observation group showed significantly lower levels of white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LYM), red blood cell count (RBC), hemoglobin (HGB), and albumin (ALB) compared to the control group (P < 0.05). …”
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8948
Table 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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8949
Data Sheet 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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8950
Table 6_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx
Published 2025“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”
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8951
Table 4_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx
Published 2025“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”
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8952
Decision curves.
Published 2025“…The observation group showed significantly lower levels of white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LYM), red blood cell count (RBC), hemoglobin (HGB), and albumin (ALB) compared to the control group (P < 0.05). …”
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8953
Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif
Published 2025“…Furthermore, ACTR6 overexpression showed a strong connection with immune cell infiltration levels and clinical and pathological factors linked to a poor prognosis. …”
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8954
Supplementary file 1_Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language...
Published 2025“…Background<p>This study evaluates how AI enhances EHR efficiency by comparing a lung cancer-specific LLM with general-purpose models (DeepSeek, GPT-3.5) and clinicians across expertise levels, assessing accuracy and completeness in complex lung cancer pathology documentation and task load changes pre−/post-AI implementation.…”
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8955
Data Sheet 1_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf
Published 2025“…Gut permeability was quantified by FITC-dextran levels in blood plasma. The cecal microbiome was identified by 16S rRNA sequencing. …”
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8956
<b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b...
Published 2025“…</p><p dir="ltr"><br></p><p dir="ltr">Furthermore, this combination elevated host GSH levels while concurrently decreasing ferrous ions, MDA, and ROS. …”
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8957
Table 1_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
Published 2025“…NEAT1 knockdown inhibited cell migration, enhanced epithelial barrier integrity, and reversed EMT-associated cytoskeletal remodeling. E-cadherin levels increased, while N-cadherin and vimentin decreased. …”
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8958
Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z...
Published 2025“…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…”
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8959
Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
Published 2025“…NEAT1 knockdown inhibited cell migration, enhanced epithelial barrier integrity, and reversed EMT-associated cytoskeletal remodeling. E-cadherin levels increased, while N-cadherin and vimentin decreased. …”
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8960
Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg
Published 2024“…Furthermore, DEX treatment reduced the expression levels of a GABA-synthesizing enzyme (GAD67), Reelin, calcium-binding proteins (parvalbumin and calretinin) and neuropeptides co-expressed in GABAergic neurons (somatostatin, neuropeptide Y and vasoactive intestinal peptide) in the PFC were reduced after 21 days of DEX treatment; these reductions were accompanied by decreases in brain size and cerebral cortex thickness.…”